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MetabolomicsTranscriptomic and Metabolomics Profiling of Phage–Host Interactions between Phage PaP1 and Pseudomonas aeruginosa
The basic biology of bacteriophage–host interactions has attracted increasing attention due to a renewed interest in the therapeutic potential of bacteriophages. In addition, knowledge of the host pathways inhibited by phage may provide clues to novel drug targets. However, the effect of phage on ba...
2018-05-03 | MTBLS431 | MetaboLights
TranscriptomicsLytic infection of Lactococcus lactis by bacteriophages Tuc2009 and c2 trigger alternative transcriptional host responses
This study analysed the temporal transcriptional response of L. lactis UC509.9 undergoing infection with either Tuc2009 or c2, representing phages of two different species (P335 and c2, respectively) of the family Siphoviridae. For the first time, to our knowledge, both DNA microarrays of the host a...
ORGANISM(S): Lactococcus lactis subsp. cremoris UC509.9 
2013-06-27 | E-GEOD-45655 | biostudies-arrayexpress
TranscriptomicsTime course of bacteriophage ?YS40 infection in wild-type and crp deletion Thermus thermophilus HB8 strain
This SuperSeries is composed of the following subset Series: GSE16954: Time course of the mRNA expression after bacteriophage ?YS40 infection in wild-type Thermus thermophilus HB8 strain. GSE16955: Time course of the mRNA expression after phage ?YS40 infection in crp deletion mutant of Thermus therm...
ORGANISM(S): Thermus thermophilus HB8 
2009-11-02 | E-GEOD-16978 | biostudies-arrayexpress
TranscriptomicsTime course of the mRNA expression after phage ϕYS40 infection in crp deletion mutant of Thermus thermophilus HB8.
We observed the expression profile of the total mRNA in crp (TTHA1437) deletion mutant strain of Thermus thermophilus HB8 during infection of bacteriophage ϕYS40. Keywords: time course, bacteriophage, infection, CRP, cAMP receptor protein, deletion mutant Three crp (TTHA1437) delection mutant strain...
ORGANISM(S): Thermus thermophilus HB8 
2009-11-02 | E-GEOD-16955 | biostudies-arrayexpress
ProteomicsInvestigating Lactococcus lactis MG1363 response to phage p2 infection at the proteome level
Phages are viruses that specifically infect and kill bacteria. Bacterial fermentation and biotechnology industries see them as enemies, however, they are also investigated for the treatment or prevention of infections caused by multidrug resistant bacteria. Whether foes or allies, their importance i...
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 Lactococcus phage 
2019-01-29 | PXD011263 | Pride
Genome editing Lactococcus lactis Label-free quantification Mass spectrometry-based proteomics Phage infection 
ProteomicsThe lactococcal phage p2 protein ORF47 impedes Lactococcus lactis MG1363 resistance to phage infection
The lactococcal phage p2 is a model for studying the Skunavirus genus, the most prevalent group of phages in cheese factories worldwide. It infects L. lactis MG1363, a model strain for the study of Gram-positive bacteria. The structural proteins of phage p2 have been thoroughly described. However, m...
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 Lactococcus phage 
2020-07-30 | PXD013186 | Pride
Lactococcus lactis Label-free quantification Mass spectrometry-based proteomics Phage infection 
TranscriptomicsTime course of the mRNA expression after bacteriophage Ï•YS40 infection in wild-type Thermus thermophilus HB8 strain.
We observed the expression profile of the total mRNA of wild-type Thermus thermophilus HB8 strain during infection of bacteriophage ϕYS40. Keywords: time course, bacteriophage, infection, wild type Three wild-type T. thermophilus HB8 strains were pre-cultured at 70°C for 16 h in 3 ml of TT medium ...
ORGANISM(S): Thermus thermophilus HB8 
2010-06-20 | E-GEOD-16954 | biostudies-arrayexpress
TranscriptomicsRNA-Seq analysis of Pseudomonas aeruginosa PAO1 cells infected with PhiKZ phage
Pseudomonas aeruginosa bacteriophage PhiKZ is the type representative of the M-bM-^@M-^XgiantM-bM-^@M-^Y phage genus with unusually large virions and genomes. By unraveling the transcriptional map of the 280 kb genome to single-nucleotide resolution, we show that it encodes 369 genes organized in 13...
ORGANISM(S): Pseudomonas aeruginosa 
2014-06-14 | E-GEOD-58494 | biostudies-arrayexpress
TranscriptomicsBacteriophage BFK 20 gene expression study
This microarray serie represents the complete gene expression study of bacteriophage BFK 20 during the infection of its host Brevibacterium flavum CCM 251. Gene expression was measured at fourteen time intervals (0, 1, 3, 5, 7, 10, 15, 20, 30, 40, 50, 60, 80 and 120 min) during phage infection accor...
ORGANISM(S): Bacteriophage BFK20 
2010-07-01 | E-GEOD-3164 | biostudies-arrayexpress
TranscriptomicsPhages DT1 and 2972 gene expression study
This series represents the gene expression study of phages DT1 and 2972 during the whole process of infection. Gene expression was measured at nine time intervals (0, 2, 7, 12, 17, 22, 27, 32, 37 minutes) during phage infection.
ORGANISM(S): Streptococcus thermophilus bacteriophage 2972 
2005-08-10 | E-GEOD-2476 | biostudies-arrayexpress
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