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The basic biology of bacteriophage–host interactions has attracted increasing attention due to a renewed interest in the therapeutic potential of bacteriophages. In addition, knowledge of the host pathways inhibited by phage may provide clues to novel drug targets. However, the effect of phage on ba...
2018-05-03 | MTBLS431 | MetaboLights
Widespread in bacteria and archaea, Toxin-antitoxin (TA) systems have been recently demonstrated to function in phage defense. Here we characterize the anti-phage function of a type IV TA system, ShosTA. Using structural and biochemical approaches, we show that ShosT couples phosphoribosyltransferas...
2025-02-17 | MTBLS11212 | MetaboLights
Identification of Serratia phage JS26 structural proteins through LC-MS/MS
ORGANISM(S): Viruses Serratia phage JS26 
2021-12-03 | PXD029878 | Pride
Pseudomonas aeruginosa bacteriophage PhiKZ is the type representative of the M-bM-^@M-^XgiantM-bM-^@M-^Y phage genus with unusually large virions and genomes. By unraveling the transcriptional map of the 280 kb genome to single-nucleotide resolution, we show that it encodes 369 genes organized in 13...
ORGANISM(S): Pseudomonas aeruginosa 
Bacteriophage lambda is one of the most extensively studied organisms, and has been a primary model for understanding basic modes of genetic regulation. Here we examine the progress of lambda gene expression during phage development by ribosome profiling, and thereby provide a very high resolution ...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
Nucleotide sequence accession number The nucleotide sequence of Escherichia virus EcS1 was deposited in the DDBJ database under accession number LC371242.
ORGANISM(S): Cellular Organisms 
Sequence overlap between two genes is common across all genomes, with viruses having particularly high proportions of these gene overlaps. The natural biological function and effects on fitness of gene overlaps are not fully understood and their effects on gene cluster and genome-level refactoring a...
ORGANISM(S): Escherichia Virus Phix174 Synthetic Enterobacteria Phage Phix174.1f 
2021-06-15 | PXD019681 | panorama
This SuperSeries is composed of the following subset Series: GSE16954: Time course of the mRNA expression after bacteriophage ?YS40 infection in wild-type Thermus thermophilus HB8 strain. GSE16955: Time course of the mRNA expression after phage ?YS40 infection in crp deletion mutant of Thermus therm...
ORGANISM(S): Thermus thermophilus HB8 
Recognition of foreign molecules inside cells is critical for immunity across all domains of life. Proteins of the STAND NTPase superfamily, including eukaryotic NOD-like receptors (NLRs), play a central role in this process. In bacteria and archaea, although several STAND families sense phage prote...
ORGANISM(S): Salmonella enterica Escherichia coli Escherichia phage T1 
2026-06-10 | PXD079457 | Pride
Jumbo phages ϕRP31/ϕRP12 infecting Ralstonia solanacearum were isolated in Thailand. Virion proteins of ϕRP31 separated by SDS-PAGE were visualized with Coomassie Brilliant Blue. The protein bands were excised from the gel, digested with trypsin, and analyzed by liquid chromatography-tandem mass spe...
ORGANISM(S): Phage 
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