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UnknownPemetrexed and cisplatin for the treatment of advanced, persistent, or recurrent carcinoma of the cervix: a limited access phase II trial of the gynecologic oncology group.
Not available
S-EPMC4145184 | biostudies-literature
UnknownAn HPLC method with diode array detector for the simultaneous quantification of chloroquine and desethylchloroquine in plasma and whole blood samples from Plasmodium vivax patients in Vietnam, using quinine as an internal standard.
Not available
S-EPMC4913743 | biostudies-literature
ProteomicsDiscovery of an ApoE4-Targeted Small-Molecule SirT1 Enhancer for the Treatment of Alzheimer’s Disease
Herein we describe the discovery of an orally brain-22 permeable small-molecule, DDL-218, that enhanced SirT1 in ApoE4-expressing neuronal cells 23 and a murine AD model. DDL-218 increased the transcription factor NFYb resulting in 24 upregulation of PRMT5. Mechanistic and modeling studies show that...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD060379 | Pride
Sirtuin 1 Prmt5 Nfyb Sirt1 Sirt1 enhancer Memory Apolipoprotein e4 
UnknownUncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool.
Not available
S-EPMC6511847 | biostudies-literature
UnknownDoes Point-of-care Ultrasonography Change Emergency Department Care Delivered to Hypotensive Patients When Categorized by Shock Type? A Post-Hoc Analysis of an International Randomized Controlled Trial from the SHoC-ED Investigators.
Not available
S-EPMC6890162 | biostudies-literature
UnknownHomeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease.
Not available
S-EPMC7529457 | biostudies-literature
UnknownAndrogenic to oestrogenic switch in the human adult prostate gland is regulated by epigenetic silencing of steroid 5α-reductase 2.
Not available
S-EPMC6212292 | biostudies-literature
UnknownDietary Pyrophosphate Modulates Calcification in a Mouse Model of Pseudoxanthoma Elasticum: Implication for Treatment of Patients.
Not available
S-EPMC6478508 | biostudies-literature
UnknownSonographic Findings of Left Ventricular Dysfunction to Predict Shock Type in Undifferentiated Hypotensive Patients: An Analysis From the Sonography in Hypotension and Cardiac Arrest in the Emergency Department (SHoC-ED) Study.
Not available
S-EPMC8360322 | biostudies-literature
UnknownDoes Point of Care Ultrasound Improve Resuscitation Markers in Undifferentiated Hypotension? An International Randomized Controlled Trial From The Sonography in Hypotension and Cardiac Arrest in the Emergency Department (SHoC-ED) Series.
Not available
S-EPMC7505535 | biostudies-literature
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