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ProteomicsEnrichment and Fragmentation Approaches for Enhanced Detection and Characterization of Endogenous Glycosylated Neuropeptides
Glycosylation, a common and heterogeneous post-translational modification plays a key role in altering biomolecule function and other properties. Prior to monitoring regulatory roles, basal glyconeuropeptide expression must be determined. Characterization is partially limited by the lower abundance ...
ORGANISM(S): Callinectes sapidus 
2022-08-19 | PXD033226 | Pride
Glycosylation Neuropeptides Endogenous peptides Mass spectrometry De novo sequencing 
ProteomicsDefinitive Screening Design to Improve Data-Independent MS Analysis of Neuropeptides
A definitive screening design was used to systematically optimize a DIA workflow for crustacean neuropeptide quantitation. We were able to assess several parameters for their effect on increasing quantifiable neuropeptides and predict the optimal value for these parameters.
ORGANISM(S): Callinectes sapidus 
2023-05-10 | PXD038520 | Pride
Design of experiments Neuropeptides Label-free quantitation Library-free 
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