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MetabolomicsAnalysis of the human adult urinary metabolome variations with age, body mass index and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. ('Sacurine' data set)

Urine metabolomics is widely used for biomarker research in the fields of medicine and toxicology. As a consequence, characterization of the variations of the urine metabolome under basal conditions becomes critical in order to avoid confounding effects in cohort studies. Such physiological infor...

2017-01-20 | MTBLS404 | MetaboLights
UnknownComplete Genome Sequence of Stenotrophomonas maltophilia Phage Philippe.
Not available
S-EPMC9202365 | biostudies-literature
MetabolomicsMetabolic fingerprinting reveals a novel candidate biomarker for prednisolone treatment in cattle
The use of glucocorticoids as growth promoters for meat-producing animals is strictly regulated within the European Union. However, in the past few years, a higher frequency of non-compliant bovine urine samples for prednisolone has been noticed, which could not be directly related to fraudulent use...
2017-01-12 | MTBLS185 | MetaboLights
MetabolomicsA metabolic dependency of EBV can be targeted to hinder B cell transformation

Following infection of B cells, Epstein Barr virus (EBV) engages host pathways that mediate cell proliferation and transformation, contributing to the propensity of the virus to drive immune dysregulation and lymphomagenesis. We found that the EBV protein EBNA2 initiates NAD de novo bios...

2024-04-29 | MTBLS2243 | MetaboLights
MetabolomicsPharmacokinetic and urinary profiling reveals prednisolone/cortisol ratio as a valid biomarker for prednisolone administration
In Europe, synthetic corticosteroids are not allowed in animal breeding fro growth-promoting purposes. Nevertheless, a high prevalence of non-compliant urine samples was recently reported for prednisolone, however, without any indication of unauthorized use. Within this context, 20b-dihydroprednisol...
2018-01-23 | MTBLS488 | MetaboLights
MetabolomicsA homeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism

Cellular senescence affects many physiological and pathological processes and is characterized by durable cell cycle arrest, an inflammatory secretory phenotype and metabolic reprogramming. Here, by using dynamic transcriptome and metabolome profiling in human fibroblasts with different subtypes ...

2024-01-09 | MTBLS7118 | MetaboLights
MetabolomicsIdentification of a discriminative metabolomic fingerprint of potential clinical relevance in saliva of patients with periodontitis using 1H nuclear magnetic resonance (NMR) spectroscopy
Periodontitis is characterized by the loss of the supporting tissues of the teeth in an inflammatory-infectious context. The diagnosis relies on clinical and X-ray examination. Unfortunately, clinical signs of tissue destruction occur late in the disease progression. Therefore, it is mandatory to id...
2018-08-14 | MTBLS524 | MetaboLights
TranscriptomicsTranscription profiling of Arabidopsis plants wounded with a cork borer
Arabidopsis plants were wounded with a cork borer to mimick insect challenge and were left for 3-5 hr before harvesting
ORGANISM(S): Arabidopsis thaliana 
2004-11-01 | E-MEXP-162 | biostudies-arrayexpress
TranscriptomicsA comprehensive map of L1HS-Ta retrotransposons in a panel of human cells obtained by ATLAS-seq.
We used ATLAS-seq to comprehensively map the genomic location of LINE-1 elements belonging to the youngest and potentially polymorphic subfamily (L1HS-Ta). This was performed in a panel of 12 human primary or transformed cell lines (BJ, IMR90, MRC5, H1, K562, HCT116, HeLa S3, HepG2, MCF7, HEK-293, H...
ORGANISM(S): Homo sapiens 
2016-05-24 | E-MTAB-4676 | biostudies-arrayexpress
ProteomicsLambert_TBX2_characterization_HEK293_P82_VS18
This set of submissions contains the mass spectrometry files by Jean-Philippe Lambert et al. that describes the functional characterization of TBX2. AP-MS and BioID experiments were performed from Flp-In T-REx HEK293 cells and MS files were acquired on 5600 TripleTOF mass spectrometers. Different M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-12-17 | MSV000086613 | MassIVE
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