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Genomic profiling of bleomycin- and saline-treated mice across 7 timepoints (1, 2, 7, 14, 21, 28, 35 days post treatment) was carried out in C57BL6/J mice to determine the phases of response to bleomycin treatment which correspond to onset of active pulmonary fibrosis. Temporal genomic characterizat...
ORGANISM(S): Mus musculus 
Polyinosinic:polycytidylic acid (poly I:C) is a synthetic analogue of double-stranded (ds)RNA, a molecular pattern associated with viral infections, that is used to exacerbate inflammation in lung injury models. Despite its frequent use, there are no detailed studies of the responses elicited by a...
ORGANISM(S): Mus musculus 
We used machine learning (ML) to improve metabolite identification confidence in GC-MS data. This project was funded by PNNL's M/Q initiative. All data was collected on an Agilent GC 7890A coupled with a single quadrupole MSD 5975C. Metabolites were derivatized prior to analysis.
ORGANISM(S): Trichoderma Reesei (ncbitaxon:51453) Aspergillus (ncbitaxon:5052) Homo Sapiens (ncbitaxon:9606) Aspergillus Nidulans (ncbitaxon:162425) 
2022-07-20 | MSV000089933 | MassIVE
Genomic profiling of RNA from cultured human fibroblasts of donor samples in the 10-14th passage was carried out to determine expression changes in the fibroblasts of individual with different degrees of pulmonary fibrosis. Donors consisted of individuals with rapid progressing pulmonary fibrosis, s...
ORGANISM(S): Homo sapiens 
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