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no omics definedTranscription profiling of Yersinia pestis wild type and phoP deletion strains
Microarrays were used to identify Y. pestis genes that are transcriptional targets of phoP. RNA samples were isolated from cultures of two isogenic Y. pestis strains, one carrying wild-type phoP (KIM6+) and the other carrying a deletion within phoP (KIM6+phoP(delta)), and their gene expression prof...
ORGANISM(S): Yersinia pestis 
2006-07-01 | E-MEXP-713 | biostudies-arrayexpress
no omics definedTranscription profiling of Yersinia pestis overexpressing phoP
Microarrays were used to identify Y. pestis genes that are differentially regulated under conditions of phoP overexpression. RNA samples were isolated from cultures of two isogenic Y. pestis strains, one overexpressing phoP (KIM10+phoP(delta)/PhoP) and the other not (KIM10+phoP(delta)/MMB67EH), and ...
ORGANISM(S): Yersinia pestis 
2006-07-01 | E-MEXP-712 | biostudies-arrayexpress
ProteomicsM. tuberculosis phoP mutant lacking mcr7
The PhoPR two-component system is essential for virulence in Mycobacterium tuberculosis where it controls expression of approximately 2% of the genes, including those for the ESX-1 secretion apparatus, a major virulence determinant. Mutations in phoP lead to compromised production of pathogen-specif...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-08-29 | PXD000698 | Pride
Mycobacterium tuberculosis Maxquant Phop Mcr7 
GenomicsThe PhoP-dependent ncRNA Mcr7 modulates the TAT secretion system in Mycobacterium tuberculosis [ChIP-Seq]
The PhoPR two-component system is essential for virulence in Mycobacterium tuberculosis where it controls expression of approximately 2% of the genes, including those for the ESX-1 secretion apparatus, a major virulence determinant. Mutations in phoP lead to compromised production of pathogen-specif...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2014-06-02 | E-GEOD-54239 | biostudies-arrayexpress
GenomicsCorynebacterium pseudotuberculosis strain:phoP
Corynebacterium pseudotuberculosis strain:phoP Genome sequencing and assembly
PRJNA371559 | ENA
TranscriptomicsComparative Genomic Analysis of PhoP Regulon in S. Typhi and S. Typhimurium
Transcriptional profiling of three sequenced S. enterica strains: S. Typhimurium LT2, S. Typhi CT18, and S. Typhi Ty2 in PhoP-inducing and non-inducing conditions in vitro, and compared these results to profiles of phoP-/Q- mutants derived from S. Typhimurium LT2 and S. Typhi Ty2. Two-condition expe...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
2010-05-06 | E-GEOD-17670 | biostudies-arrayexpress
TranscriptomicsThe PhoP-dependent ncRNA Mcr7 modulates the TAT secretion system in Mycobacterium tuberculosis [RNA-Seq]
The PhoPR two-component system is essential for virulence in Mycobacterium tuberculosis where it controls expression of approximately 2% of the genes, including those for the ESX-1 secretion apparatus, a major virulence determinant. Mutations in phoP lead to compromised production of pathogen-specif...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2014-06-02 | E-GEOD-54240 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of Streptomyces coelicolor wild type and phP-null mutants during phosphate starvation to determine binding locations of PhoP
S. coelicolor was grown in low-phosphate concentration R5 liquid medium which facilitated the transition to a phosphate starvation induced stationary phase and the subsequent induction of the PhoP regulon. The genome wide binding locations of PhoP during phosphate starvation were determined by chrom...
ORGANISM(S): Streptomyces coelicolor 
2012-08-30 | E-MAXD-50 | biostudies-arrayexpress
TranscriptomicsMetabolic switches and adaptations deduced from the proteomes of Streptomyces coelicolor wild type and phoP mutant grown in batch culture
Bacteria in the genus Streptomyces are soil dwelling oligotrophs and important producers of secondary metabolites. Previously we showed that global mRNA expression was subject to a series of metabolic and regulatory switches during the life time of a fermentor batch culture of S. coelicolor M145. He...
ORGANISM(S): Streptomyces coelicolor 
2011-12-31 | E-GEOD-31068 | biostudies-arrayexpress
GenomicsComparative Genomic Analysis of PhoP Regulon in S. Typhi and S. Typhimurium
Comparative Genomic Analysis of PhoP Regulon in S. Typhi and S. Typhimurium
PRJNA118477 | ENA
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