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ProteomicsSMARCA4 Phosphorilation inhibition
Cyclin-Dependent Kinase 9 (CDK9) as part of the PTEFb complex promotes transcriptional elongation and high-level gene expression. We now report that, paradoxically, CDK9 is also essential for maintaining gene silencing at heterochromatic loci. Through a live cell screen, we discovered that CDK9 inhi...
ORGANISM(S): Homo sapiens (Human) 
2023-06-13 | PXD008040 | Pride
Phosphoproteomics Colon cancer cells Lc-ms/ms 
GenomicsTranscriptional profiling reveals an upregulation of genes related to Sphingolipid metabolism and Oxidative phosphorilation in HRas and NRas double-KO mice (DKO), which die because of a severe respiratory distress
Transcriptional profiling reveals an upregulation of genes related to Sphingolipid metabolism and Oxidative phosphorilation in HRas and NRas double-KO mice (DKO), which die because of a severe respiratory distress
PRJNA772757 | ENA
GenomicsTranscriptional profiling reveals an upregulation of genes related to Sphingolipid metabolism and Oxidative phosphorilation in HRas and NRas double-KO mice (DKO), which die because of a severe respiratory distress.
Transcriptional profiling reveals an upregulation of genes related to Sphingolipid metabolism and Oxidative phosphorilation in HRas and NRas double-KO mice (DKO), which die because of a severe respiratory distress.
PRJNA540213 | ENA
TranscriptomicsMetabolite and transcript profiling of VvERF045 OE transgenic lines elucidate the role of this transcription factor in the grapevine ripening physiology
We report the transcriptomic profile of L15, a transgenic line overexpressing VvERF045, and the WT as a reference. The main aim is to understand the function of this transcription factor in the overall plant though the differences in the transcript abundance (RNA-seq) and metabolite production. Tota...
ORGANISM(S): Vitis vinifera 
2016-07-01 | GSE77240 | GEO
TranscriptomicsMetabolite and transcript profiling of VvERF045 OE transgenic lines elucidate the role of this transcription factor in the grapevine ripening physiology
We report the transcriptomic profile of L15, a transgenic line overexpressing VvERF045, and the WT as a reference. The main aim is to understand the function of this transcription factor in the overall plant though the differences in the transcript abundance (RNA-seq) and metabolite production. To...
ORGANISM(S): Vitis vinifera 
2016-07-01 | E-GEOD-77240 | biostudies-arrayexpress
UnknownTranscriptomic integration of D4R and MOR signaling in the rat caudate putamen.
Not available
S-EPMC5943359 | biostudies-literature
UnknownTherapeutic efficacy of SYM004, a mixture of two anti-EGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation.
Not available
S-EPMC5620195 | biostudies-literature
UnknownIdentification and characterization of a novel nasopharyngeal carcinoma-associated peptide: NAP-1.
Not available
S-EPMC411061 | biostudies-literature
UnknownLASSBio-1135: a dual TRPV1 antagonist and anti-TNF-alpha compound orally effective in models of inflammatory and neuropathic pain.
Not available
S-EPMC4062389 | biostudies-literature
TranscriptomicsTranscriptional profiling reveals an upregulation of genes related to Sphingolipid metabolism and Oxidative phosphorilation in HRas and NRas double-KO mice (DKO), which die because of a severe respiratory distress
We used microarrays to investigate gene expression changes in the lungs of Control, Hras-KO, Nras-KO and DKO mice. These DKO animals die at birth because of respiratory distress, caused by an impaired lung maturation. N-acetyl cysteine antenatal treatment ameliorates the newborn lethality.
ORGANISM(S): Mus musculus 
2021-10-22 | GSE186161 | GEO
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