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TranscriptomicsLow-power photodynamic therapy induces survival signaling in cultured hilar cholangiocarcinoma cells
Photodynamic therapy (PDT) of solid cancers comprises the administration of a photosensitizer followed by illumination of the photosensitizerreplete tumor with laser light. This induces a state of local oxidative stress, culminating in the destruction of tumor tissue and microvasculature and inducti...
ORGANISM(S): Homo sapiens 
2016-01-04 | E-GEOD-68292 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of 4T1 murine breast carcinoma cells and derived cell lines resistant to photodynamic therapy induced by novel porphyrin-based photosensitizers and temoporfin
The efficacy of photodynamic therapy for treating premalignant and malignant tumors is often limited by the emerging resistant tumor cells. We have developed experimental model systems to study the mechanisms associated with resistance to photodynamic therapy induced by structurally similar photosen...
ORGANISM(S): Mus musculus 
2017-06-14 | E-MTAB-5082 | biostudies-arrayexpress
MetabolomicsSono-Photodynamic Treatment Induces Bidirectional Changes in Flavor Quality of Fried Low-Salt Large Yellow Croaker (Larimichthys crocea) During Early Refrigerated Storage (MS (MTBLS))
Using low-salt large yellow croaker as the research subject, this study introduced curcumin-mediated sonodynamic and photodynamic treatment (SPDT) to investigate shelf-life extension and flavor quality preservation. Microbial community analysis revealed that SPDT inhibited specific spoilage organism...
2026-09-18 | MTBLS15718 | MetaboLights
ProteomicsChemoproteomics analysis revealed photodynamic therapy (PDT) effect of Novel Photo-switchable Photosensitizer
The study titled "Dyad system of BOAHY-BODIPY Conjugates as Novel Photo-switchable Photosensitizer for Photodynamic Therapy" investigated the photodynamic therapy (PDT) potential of a compound that switches structures (Z form to E form) under UV irradiation. The compound generates reactive oxygen sp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-13 | MSV000096072 | MassIVE
GenomicsPhotodynamic oncolytic virus therapy for central nervous system malignancies
Photodynamic oncolytic virus therapy for central nervous system malignancies
PRJNA923791 | ENA
ProteomicsStudy of reversible oxidation of thiol proteins after hexyl aminolevulinate mediated photodynamic therapy
This proteomic study This proteomic study focuses on the role of reversible thiol oxidation after hexyl aminolevulinate mediated PDT (HAL-PDT). The human epidermoid carcinoma cell line A431 was used as model system and red light as light source, a clinical relevant in vitro model. The light dose dep...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080866 | MassIVE
TranscriptomicsTranscription profiling by array of human T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
Study of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
ORGANISM(S): Homo sapiens 
2007-10-01 | E-MEXP-1220 | biostudies-arrayexpress
UnknownSonodynamic therapy in combination with photodynamic therapy shows enhanced long-term cure of brain tumor.
Not available
S-EPMC7732989 | biostudies-literature
GenomicsTranscriptomic analysis of mouse brain tissue treated by 5-ALA-mediated photodynamic therapy
Transcriptomic analysis of mouse brain tissue treated by 5-ALA-mediated photodynamic therapy
PRJNA726288 | ENA
TranscriptomicsPhotodynamic oncolytic virus therapy for central nervous system malignancies
The goal of the study was to determine whether photodynamic oncolytic virus therapy of glioblastoma and malignant meningioma xenografts in mice alters transciptomics associated with efficacy. RNA sequencing was used from tumors treated with PBS, laser, G47delta-KillerRed, and G47delta-KillerRed and ...
ORGANISM(S): Homo sapiens 
2023-01-18 | GSE222895 | GEO
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