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ProteomicsDisruption of Heme Uptake and PrrF sRNA Expression in the Pseudomonas aeruginosa PhuS H209A Variant Induces a Metabolic Stress-Response
The Pseudomonas aeruginosa heme-binding protein PhuS plays a central role in coordinating heme utilization with iron homeostasis through the PrrF small RNAs. Proteomic and metabolomic analyses of the phuSH209A allelic strain demonstrated that the previously characterized in vitro disruption of PhuS ...
ORGANISM(S): Pseudomonas aeruginosa PA103 
2026-09-28 | PXD079786 | Pride
Heme-binding protein Pseudomonas aeruginosa Prrf small rnas Phus H209a variant 
UnknownFunction Coupling Mechanism of PhuS and HemO in Heme Degradation.
Not available
S-EPMC5596023 | biostudies-literature
UnknownModeling the native ensemble of PhuS using enhanced sampling MD and HDX-ensemble reweighting.
Not available
S-EPMC8715216 | biostudies-literature
UnknownCrystal structure of the Pseudomonas aeruginosa cytoplasmic heme binding protein, Apo-PhuS.
Not available
S-EPMC3843485 | biostudies-literature
UnknownThe heme-binding protein PhuS transcriptionally regulates the Pseudomonas aeruginosa tandem sRNA prrF1,F2 locus.
Not available
S-EPMC7948967 | biostudies-literature
UnknownInduced fit on heme binding to the Pseudomonas aeruginosa cytoplasmic protein (PhuS) drives interaction with heme oxygenase (HemO).
Not available
S-EPMC3326490 | biostudies-literature
UnknownThe P. aeruginosa heme binding protein PhuS is a heme oxygenase titratable regulator of heme uptake.
Not available
S-EPMC3748626 | biostudies-literature
UnknownThe role of the cytoplasmic heme-binding protein (PhuS) of Pseudomonas aeruginosa in intracellular heme trafficking and iron homeostasis.
Not available
S-EPMC2610525 | biostudies-literature
UnknownThe Pseudomonas aeruginosa PhuS proximal ligand His-209 triggers a conformational switch in function from DNA binding to heme transfer.
Not available
S-EPMC12033910 | biostudies-literature
UnknownThe mechanism of heme transfer from the cytoplasmic heme binding protein PhuS to the delta-regioselective heme oxygenase of Pseudomonas aeruginosa.
Not available
S-EPMC2631378 | biostudies-literature
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