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MetabolomicsTrans-tissue molecular coordination in high-intensity physical activity
High-intensity physical activity has major impacts in different parts of the body. However, the regulatory coordination between different tissues to support the high physical demands is poorly understood. Here we performed a multi-omics analysis of blood plasma, urine and saliva from a group of fire...
2025-07-03 | MTBLS1891 | MetaboLights
TranscriptomicsGene expression changes in Peripheral Blood Mononuclear cells (PBMC) induced by physical activity
Gene expression changes in Peripheral Blood Mononuclear cells (PBMC) induced by physical activity was investigated in sedentary middle-aged men (mean age 52.6 years and BMI 29.1) who undertook a 24-week physical activity programme with blood sampling in the pre-exercise period , at the end of 24-w...
ORGANISM(S): Homo sapiens 
2010-08-03 | E-GEOD-12385 | biostudies-arrayexpress
MetabolomicsDiscovery of isokurarinone as an ATCase-Engaging Lead with potent activity against methicillin-resistant Staphylococcus aureus

The global proliferation of methicillin-resistant Staphylococcus aureus (MRSA) persists as a significant contributor to challenging infections, highlighting the urgent necessity for therapies that utilize novel mechanisms. Aspartate transcarbamoylase (ATCase), which catalyzes the initial committe...

2026-01-14 | MTBLS13673 | MetaboLights
TranscriptomicsEffect of IL6 level on gene expression changes in Peripheral Blood Mononuclear cells (PBMC) induced by physical activity
A number of chronic, age-related diseases are associated with elevated markers of inflammation such as interleukin-6 (IL-6). In this study, we investigated the hypothesis that sedentary individuals with disparate basal serum IL-6 respond differentially to a structured physical activity programme. Ge...
ORGANISM(S): Homo sapiens 
2010-08-03 | E-GEOD-12384 | biostudies-arrayexpress
UnknownBarriers and facilitators to implementing community-based physical activity interventions: a qualitative systematic review.
Not available
S-EPMC8422651 | biostudies-literature
UnknownPhysical Activity, Injurious Falls, and Physical Function in Aging: An Umbrella Review.
Not available
S-EPMC6527126 | biostudies-literature
UnknownWhat hinders and helps academics to conduct Dissemination and Implementation (D&I) research in the field of nutrition and physical activity? An international perspective.
Not available
S-EPMC6966833 | biostudies-literature
UnknownMacroeconomic, demographic and human developmental correlates of physical activity and sitting time among South American adults.
Not available
S-EPMC7737374 | biostudies-literature
ProteomicsA microbiome-dependent gut brain pathway regulates motivation for exercise
Exercise exerts a wide range of beneficial effects for healthy physiology. However, the mechanisms regulating an individual's motivation to engage in physical activity remain incompletely understood. An important factor stimulating the engagement in both competitive and recreational exercise is the ...
ORGANISM(S): Mouse 
2023-03-15 | MSV000091494 | MassIVE
MetabolomicsBiological Potential of Lophosoria quadripinnata Fern Extract: Integration of UHPLC/ESI/QToF/MS Analysis, Antioxidant Activity, Molecular Docking and Molecular Dynamics Simulation

Lophosoria quadripinnata (J.F.Gmel.) C.Chr., a fern species from the Dicksoniaceae family, is widely distributed in Central and South America. This study aimed to identify the bioactive compounds in the aqueous extract of L. quadripinnata, evaluate its antioxidant potential through in vitro analy...

2025-06-27 | MTBLS9336 | MetaboLights
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