Sort   by:  
 Page size 
UnknownAssociation of sirolimus adverse effects with m-TOR, p70S6K or Raptor polymorphisms in kidney transplant recipients.
Not available
S-EPMC3894420 | biostudies-literature
GenomicsVitamin C induces Tet-dependent DNA demethylation in ES cells to promote a blastocyst-like methylome [MeDIP-Seq]
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in the early embryo and the germline and may be mediated by Tet (ten-eleven-translocation) enzymes, which convert 5-methylcytosine (...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-46402 | biostudies-arrayexpress
UnknownTargeted long-read sequencing identifies missing pathogenic variants in unsolved Werner syndrome cases.
Not available
S-EPMC9613861 | biostudies-literature
TranscriptomicsATAC-seq of C3H mouse livers
This study aims to investigate the interactions of mutagenic lesions from diethylnitrosamine (DEN) treatment of mouse livers with such processes as replication, transcription, and interaction of DNA with proteins. Liver samples of 15-day old (P15) untreated C3H/HeOuJ mice were isolated and flash-fro...
ORGANISM(S): Mus musculus 
2023-04-25 | E-MTAB-11780 | biostudies-arrayexpress
TranscriptomicsGlobal Run-On sequencing (GRO-seq) of HeLa cells under CDK9 inhibitor tratment to study elongation checkpoints at both ends of RNA polymerase II-transcribed genes.
Global Run-On sequencing (GRO-seq) was carried out on nuclei isolated from HeLa cells after 30 minutes of treatment with CDK9 inhibitors KM05382 and DRB and from two untreated controls. Libraries of nascent RNAs were generated and sequenced using Illumina Hi-seq technology. GRO-seq reads were proces...
ORGANISM(S): Homo sapiens 
2015-02-26 | E-MTAB-3360 | biostudies-arrayexpress
UnknownApplication of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons.
Not available
S-EPMC7322529 | biostudies-literature
TranscriptomicsATAC-seq of wild-type, Pbx1/Pbx2 double-knockout and pMsgn1-mut EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 48 hours of differentiation.
In vertebrates, body axis elongation is fuelled by bipotent neuromesodermal progenitors (NMPs), which support the development of both spinal cord and paraxial mesoderm (PM). WNT signalling sustains both NMP expansion and PM differentiation, but the mechanism by which it distinguishes between these a...
ORGANISM(S): Mus musculus 
2021-07-21 | E-MTAB-9776 | biostudies-arrayexpress
UnknownYBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA.
Not available
S-EPMC7352269 | biostudies-literature
UnknownPhage susceptibility testing and infectious titer determination through wide-field lensless monitoring of phage plaque growth.
Not available
S-EPMC7987195 | biostudies-literature
UnknownFactors Predicting the Presence of Maternal Cells in Cord Blood and Associated Changes in Immune Cell Composition.
Not available
S-EPMC8100674 | biostudies-literature
Sort   by:  
 Page size