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TranscriptomicsSingle cell RNA-sequencing of human tonsil Innate lymphoid cells (ILCs)
Single cell RNA-sequencing of human tonsil Innate lymphoid cells (ILCs) from three independent tonsil donors. Sequencing libraries were prepared from FACS sorted individual ILCs with the Smart-Seq2 protocol (Picelli et al. Nature Methods 2013)
ORGANISM(S): Homo sapiens 
2016-01-27 | E-GEOD-70580 | biostudies-arrayexpress
TranscriptomicsThe transcriptional landscape of mouse blood stem/progenitor cell transitions at single cell resolution
Current gene-expression databases for the haematopoietic system provide information on gene expression profiles present in bulk populations. Although informative, these studies lack the resolution that can be gained at a single-cell level. In particular, population-average data assumes homogeneity w...
ORGANISM(S): Mus musculus 
2016-07-04 | E-GEOD-81682 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing of human embryonic stem cell-derived pancreatic cells enriched for early endocrine progenitors using a novel dual NEUROG3-reporter
Human embryonic stem cells with one allele of the NEUROG3 gene genetically modified into a fusion gene NEUROG3-LINKER-TAGRFPT-P2A-EGFP-NLS were differentiated into the pancreatic lineage until Stage 4 Day 1 of the in vitro differentiation protocol (Rezania et al., 2014, as modified in Petersen et al...
ORGANISM(S): Homo sapiens 
2022-12-31 | E-MTAB-11208 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA-seq analysis of human pancreas from healthy individuals and type 2 diabetes patients
We used single-cell RNA-sequencing to generate transcriptional profiles of endocrine and exocrine cell types of the human pancreas. Pancreatic tissue and islets were obtained from six healthy and four T2D cadaveric donors. Islets were cultured and dissociated into single-cell suspension. Viable indi...
ORGANISM(S): Homo sapiens 
2016-09-22 | E-MTAB-5061 | biostudies-arrayexpress
TranscriptomicsGene expression changes associated with kinase-inactivated Cdk6 or a complete Cdk6 KO in mouse HSC/MPP1 cells after two rounds of transplantation
A kinase-inactivated variant of Cdk6 (Cdk6_K43M) was associated with prolonged repopulation potential of mouse lineage-negative, Sca1-positive, cKit-positive, CD150-positive, CD48-negative (HSC/MPP1) cells. In order to understand differences between Cdk6_K43M HSC/MPP1 cells, and HSC/MPP1 cells carry...
ORGANISM(S): Mus musculus 
2024-05-22 | E-MTAB-13145 | biostudies-arrayexpress
UnknownQuantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study.
Not available
S-EPMC5892248 | biostudies-literature
UnknownCharacterization of cyantraniliprole resistance in Spodoptera frugiperda: Selection, inheritance pattern, and cross-resistance to other diamide insecticides.
Not available
S-EPMC12268807 | biostudies-literature
UnknownNano-optomechanical fiber-tip sensing.
Not available
S-EPMC11879848 | biostudies-literature
TranscriptomicsMyeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence
Tissue stem cells are hierarchically organized, but the signals that selectively preserve their functional integrity are largely unknown. Semaphorin 4A (Sema4A) is a specific regulator of myeloid-biased hematopoietic stem cells (myHSC), which are positioned at the top of the HSC hierarchy. Through s...
ORGANISM(S): Mus musculus 
2023-06-04 | E-MTAB-12890 | biostudies-arrayexpress
UnknownCall for founding members of the European Organization For University Physical and Rehabilitation Medicine (UniPRM).
Not available
S-EPMC12421331 | biostudies-literature
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