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ProteomicsProteomics analysis of monocyte-derived hepatocyte-like cells identifies integrin beta 3 as a specific biomarker for drug-induced liver injury by diclofenac
Idiosyncratic drug-induced liver injury (iDILI) is a major cause of acute liver failure resulting in liver transplantation or death. Prediction and diagnosis of iDILI remain a great challenge, as current models provide unsatisfying results in terms of sensitivity, specificity and prognostic value. T...
ORGANISM(S): Homo sapiens (Human) 
2018-07-23 | PXD008918 | Pride
Dili Monocyte.derived hepatocyte-like cells Drug-development Proteomics Biomarker 
ProteomicsUltra-deep and quantitative saliva proteome reveals dynamics of the oral microbiome
The oral cavity is home to one of the most diverse microbial community of the human body and a major entry portal for pathogens. Its homeostasis is maintained by saliva, which fulfills key functions including lubrication of food, predigesting and bacterial defense. Consequently, disruptions in saliv...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080862 | MassIVE
ProteomicsH.sapiens - Cell line, SC (Kulaketal,natmethods2014)
abundance based on Spectral counting, Interaction consistency score: 12.4, Coverage: 7
ORGANISM(S): 9606 
2014-00-00 | 1861201586 | PAXDB
ProteomicsS.cerevisiae - Whole organism, SC (Kulaketal,natmethods2014)
abundance based on Spectral counting, Interaction consistency score: 22.1, Coverage: 68
ORGANISM(S): 4932 
2014-00-00 | 1072451528 | PAXDB
ProteomicsS.pombe - Whole organism, SC (Kulaketal,natmethods2014)
abundance based on Spectral counting, Interaction consistency score: 15.4, Coverage: 33
ORGANISM(S): 4896 
2014-00-00 | 2189306272 | PAXDB
ProteomicsH.sapiens - Saliva, iBAQ (Grassletal,genomemed2016)
abundance based on iBAQ, Interaction consistency score: 13.6, Coverage: 27
ORGANISM(S): 9606 
2016-00-00 | 1356012761 | PAXDB
ProteomicsH.sapiens - Plasma, iBAQ (Grassletal,genomemed2016)
abundance based on iBAQ, Interaction consistency score: 2.7, Coverage: 1
ORGANISM(S): 9606 
2016-00-00 | 2304673249 | PAXDB
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