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MetabolomicsTissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and treatment
The discovery of the oncometabolite 2-hydroxyglutarate in isocitrate dehydrogenase 1-mutated (IDH1-mutated) tumor entities affirmed the role of metabolism in cancer. However, large databases with tissue metabolites that are modulated by IDH1 mutation remain an area of development. Here, we present a...
2022-09-07 | MTBLS3873 | MetaboLights
UnknownForecasting the propagation of pandemic shocks with a dynamic input-output model.
Not available
S-EPMC9472492 | biostudies-literature
ProteomicsSystematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis
We previously reported that Parkinson’s disease (PD) kinase LRRK2 phosphorylates a subset of Rab GTPases on a conserved residue in their switch-II domains (Steger, Tonelli et al., 2016) (PMID: 26824392). Here, we systematically analyzed the Rab protein family and found 14 of them (Rab3A/B/C/D, Rab5A...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2017-11-14 | PXD007214 | Pride
Proteomics Rabgtpases Lrrk2 Parkinson's disease 
UnknownValidation of the pretreatment derived neutrophil-lymphocyte ratio as a prognostic factor in a European cohort of patients with upper tract urothelial carcinoma.
Not available
S-EPMC4021523 | biostudies-literature
UnknownEnhancing Transsectoral Interdisciplinary Patient-Centered Care for Patients With Rare Cancers: Protocol for a Mixed Methods Process Evaluation.
Not available
S-EPMC10603554 | biostudies-literature
GenomicsIdentification of mutations and structural rearrangements in plasma DNA form metastatic prostate cancer patients
In this study we analysed patients with metastatic prostate cancer to scan their tumor genomes noninvasively in plasma DNA. We enriched 1.3 Mbp of seven plasma DNAs (4 CRPC cases: CRPC1-3 and CRPC5; 3 CSPC cases: CSPC1-2 and CSPC4) including exonic sequences of 55 cancer genes and 38 introns of 18 g...
EGAS00001000453 | EGA
Genomicsena-DATASET-MUG-26-02-2014-10:25:52:632-26 - samples
In this study we performed whole genome sequencing of plasma DNA (plasma-Seq) of 19 plasma-DNA samples from a total of 10 patients treated with anti-EGFR therapy. We demonstrated that development of resistance to anti-EGFR therapies is frequently associated with focal amplifications of KRAS, MET, an...
EGAD00001000748 | EGA
Genomicsena-DATASET-MUG-19-03-2013-14:10:31:964-87 - samples
We performed low coverage whole genome sequencing of plasma DNA from prostate cancer patients to establish copy number profiles on both a genome-wide and a gene-specific level. The data include plasma samples from prostate cacner patients (n=13), non-malignant controls (males, n=10 and females, n=9)...
EGAD00001000364 | EGA
Genomicsena-DATASET-MUG-29-10-2013-10:52:10:827-14 - samples
In this study we performed ultra deep sequencing of genes associated with anti-EGFR resistance, such as KRAS, BRAF, PIK3CA, and EGFR in 17 plasma-DNA samples from a total of 10 patients treated with anti-EGFR therapy.
EGAD00001000688 | EGA
Genomicsena-DATASET-MUG-19-03-2013-14:14:47:994-92 - samples
In this study we analysed patients with metastatic prostate cancer to scan their tumor genomes noninvasively in plasma DNA. We enriched 1.3 Mbp of seven plasma DNAs (4 CRPC cases: CRPC1-3 and CRPC5; 3 CSPC cases: CSPC1-2 and CSPC4) including exonic sequences of 55 cancer genes and 38 introns of 18 g...
EGAD00001000365 | EGA
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