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MetabolomicsGallbladder microbial species and host bile acids biosynthesis linked to cholesterol gallstone comparing to pigment individuals

Gallstones are crystalline deposits in the gallbladder that are traditionally classified as cholesterol, pigment or mixed stones based on their composition. Microbiota and host metabolism variances among the different types of gallstones remain largely unclear. Here, the bile and gallstone microb...

2024-03-11 | MTBLS7736 | MetaboLights
Proteomicscryo-EM study of bovine retinal pigment epithelium cell lysate
This is the proteomic analysis data of bovine retinal pigment epithelium cell lysate subjected to cryo-EM study.
ORGANISM(S): Bos taurus (Bovine) 
2023-01-02 | PXD037186 | Pride
Cryo-em Bovine Retinal pigment epithelium cell 
TranscriptomicsIdentification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells
Retinal pigment epithelium (RPE) cells can be obtained through in vitro differentiation of both embryonic stem cell (ESC) and induced pluripotent stem cells (iPSC) for cell replacement therapy. We have previously identified 87 signature genes relevant to RPE cell differentiation and function through...
ORGANISM(S): Homo sapiens 
2012-08-01 | E-GEOD-37686 | biostudies-arrayexpress
TranscriptomicsWild type V. cholerae strain A1552 growth time course in AKI media
We identified the mutated gene locus in a pigment overproducing Vibrio cholerae mutant of strain A1552. The deduced gene product is suggested to be a oxidoreductase based on partial homology to putative homogentisate 1,2-dioxygenase in Pseudomonas aeruginosa and Mesorhizobium loti and we propose tha...
ORGANISM(S): Vibrio cholerae 
2009-01-20 | E-GEOD-14360 | biostudies-arrayexpress
TranscriptomicsFunctional Retinal Pigment Epithelium-like Cells from Human Fibroblasts
The retinal pigment epithelium (RPE) provides vital support to photoreceptor cells and its dysfunction is associated with the onset and progression of age-related macular degeneration (AMD). Surgical provision of RPE cells may ameliorate AMD and thus it would be valuable to develop sources of patien...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-64264 | biostudies-arrayexpress
MetabolomicsIdentification of pre-diagnostic lipid sets associated with liver cancer risk using untargeted lipidomics and chemical set analysis – a nested case-control study within the ATBC cohort

In pre-disposed individuals, a reprogramming of the hepatic lipid metabolism may support liver cancer initiation. We conducted a high-resolution mass spectrometry based untargeted lipidomics analysis of pre-diagnostic serum samples from a nested case-control study (219 liver cancer cases and 219 ...

2023-09-18 | MTBLS7776 | MetaboLights
ProteomicsProteomic analysis of S-acylated proteins in human retinal pigment epithelial cells reveals the role of palmitoylation of Niemann–Pick type C1 protein in cholesterol transportation
Palmitoylation is a dynamic process which regulates the activity of the modified proteins. Retinal pigment epithelial (RPE) cells play pivotal roles in visual cycle and maintaining healthy photoreceptor cells. Dysfunctional RPE cells are often associated with degenerative retinal diseases. The aim o...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD034896 | Pride
Niemann-pick type c1 protein Retinal pigment epithelial cells Palmitoylation 
TranscriptomicsCharacterization of the melanoma miRNAome by deep sequencing
MicroRNAs are 18-23 nucleotide non-coding RNAs that regulate gene expression in a sequence specific manner. Little is known about the repertoire and function of miRNAs in melanoma or the melanocytic lineage. We therefore undertook a comprehensive analysis of the miRNAome in a diverse range of pigmen...
ORGANISM(S): Homo sapiens 
2010-03-22 | E-GEOD-18381 | biostudies-arrayexpress
UnknownIdentification of the orange pigment in Nonomuraea gerenzanensis and development of a pigment-free mutant.
Not available
S-EPMC12804471 | biostudies-literature
GenomicsIdentification of cell surface markers and establishment of monolayer differentiation protocol for retinal pigment epithelial cells.
Identification of cell surface markers and establishment of monolayer differentiation protocol for retinal pigment epithelial cells.
PRJEB31931 | ENA
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