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TranscriptomicsMethylation array profiling of undifferentiated sarcomas of adults
Profiling the methylation landscape of undifferentiated sarcomas. Comparisons to be made with publically available methylation datasets of other sarcomas.
ORGANISM(S): Homo sapiens 
2019-04-02 | E-MTAB-6961 | biostudies-arrayexpress
TranscriptomicsAn integrated functional genomics approach identifies the regulatory network directed by brachyury in chordoma
shRNA-mediated brachyury knockdown was performed on the chordoma cell line U-CH1 as replicates. RNA was extracted, labelled and hybridised to Human Gene 1.0ST chips followed by gene expression microarray analysis.This was followed by a ChIP-seq experiment using a specific brachyury antibody, the dat...
ORGANISM(S): Homo sapiens 
2012-10-08 | E-MEXP-3716 | biostudies-arrayexpress
TranscriptomicsA common single nucleotide variant in T is strongly associated with chordoma
Gene expression profile of human chordoma samples. These samples were combined with the chordoma samples from those of E-MEXP-353. These were normalised and batch corrected as per materials and methods in the published paper. Gene set enrichment analysis was then performed to determine enrichment o...
ORGANISM(S): Homo sapiens 
2013-08-20 | E-MEXP-3717 | biostudies-arrayexpress
TranscriptomicsArrayCGH study to investigate duplication of T locus in chordoma
Duplication of T is a known familial susceptibility determinant for chordoma. TO determine if a similar genetic alteration occurs in the sporadic disease a high-resolution array-CGH (Agilent custom-designed arrayCGH chip) was used to interrogate the chr 6q27 locus for duplication of T. Twenty two sa...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-MEXP-3753 | biostudies-arrayexpress
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