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Synergistic Mn-MOF Activation of Pistol Ribozymes for Cancer Immunotherapy
Checkpoint blockade therapies targeting PD-L1 have revolutionized cancer immunotherapy, yet their efficacy is constrained by systemic immune toxicity and inadequate immune infiltration in certain tumor types. Here, we introduce a synergistic gene-silencing nanosystem based on a target-selective Pist...
ORGANISM(S): Mus musculus 
2026-01-01 | GSE302201 | GEO
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