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TranscriptomicsTranscription profiling by array of human ovarian cancer cells overexpressing PKA regulatory subunits
The regulatory subunit of cAMP-dependent protein kinase (PKA) exists in two isoforms, RI and RII, which distinguish the PKA isozymes, type I (PKA-I) and type II (PKA-II). Evidence obtained from a variety of different experimental approaches has shown that the relative levels of type I and type II PK...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-12854 | biostudies-arrayexpress
TranscriptomicsRNA-Seq profiling of C2C12 cells with exogenous expression of Mef2Da1 and Mef2Da2
Although splicing occurs in most multi-exon genes, the generation of distinct isoforms through the alternate use of mutually exclusive exons is less prevalent. As exon-switching events have the potential to give rise to isoforms with different cellular functions, we have explored the role of the mus...
ORGANISM(S): Mus musculus 
2013-06-03 | E-GEOD-46363 | biostudies-arrayexpress
ProteomicsYeast PKA holoenzyme and condensate targeted and label-free proteomics
Protein kinase A (PKA) is a conserved kinase essential for many biological processes linked to growth, development and metabolism. The PKA catalytic subunit is expressed as multiple isoforms in diverse eukaryotes; however, their contribution to ensuring specificity in response to environmental cues ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-09-19 | PXD045310 | Pride
Holoenzyme Yeast Condensates Heat stress Pka isoforms 
UnknownEvolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms.
Not available
S-EPMC5526564 | biostudies-literature
ProteomicsIdentification and phosphorylation site mapping of a sperm specific PKA C subunit isoform from Mytilus galloprovincialis
This project investigates a sperm-specific isoform of the catalytic (C) subunit of cAMP-dependent protein kinase (PKA) in the marine mussel Mytilus galloprovincialis, an externally fertilizing invertebrate widely used as a model for gamete activation studies. A C-subunit isoform purified from male g...
ORGANISM(S): Crenomytilus 
2026-09-07 | PXD076788 | Pride
Camp-dependent protein kinase  pka  catalytic subunit  lc–ms/ms  phosphoproteomics  phosphorylation sites  tio₂ enrichment  mytilus galloprovincialis  sperm 
TranscriptomicsOverexpression of PKA regulatory subunits in ovarian cancer cells
The regulatory subunit of cAMP-dependent protein kinase (PKA) exists in two isoforms, RI and RII, which distinguish the PKA isozymes, type I (PKA-I) and type II (PKA-II). Evidence obtained from a variety of different experimental approaches has shown that the relative levels of type I and type II PK...
ORGANISM(S): Homo sapiens 
2008-09-20 | GSE12854 | GEO
UnknownLocalization and quaternary structure of the PKA RIβ holoenzyme.
Not available
S-EPMC3411989 | biostudies-literature
TranscriptomicsGlobal regulatory roles of the cAMP/PKA pathway revealed by phenotypic, transcriptomic, and phosphoproteomic analyses in a null mutant of PKA catalytic subunit in Candida albicans
The conserved cAMP-dependent protein kinase (PKA) holoenzyme is composed of two catalytic and two regulatory subunits. It plays critical roles in the regulation of many biological processes in eukaryotic organisms. In the human fungal pathogen Candida albicans, the PKA kinase has been extensively in...
ORGANISM(S): Candida albicans 
2017-08-18 | GSE92621 | GEO
UnknownInvestigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2.
Not available
S-EPMC5844854 | biostudies-literature
UnknownKChIP4a regulates Kv4.2 channel trafficking through PKA phosphorylation.
Not available
S-EPMC2823810 | biostudies-literature
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