Sort   by:  
 Page size 
TranscriptomicsPKA-dependent Phosphorylation of A Histone Demethylase Drives Higher Order Chromatin Structures by Association with SWI/SNF Chromatin Remodeler
The current studies show that JMJD1A is phosphorylated at S265 by protein kinase A (PKA), and this is pivotal to activate expression of the b1-adrenergic receptor gene (Adrb1) and downstream targets including Ucp1. Phosphorylation of JMJD1A increases its interaction with the SWI/SNF nucleosome remod...
ORGANISM(S): Mus musculus 
2015-04-15 | E-GEOD-58936 | biostudies-arrayexpress
ProteomicsIdentification of PKA dependent phosphorylation sites
Identification of PKA dependent phosphorylation sites in Exponential, starvation (day 8) and heat shock conditions.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-06-20 | PXD052971 | Pride
Pka inhibition Phosphorylation 
ProteomicsPhosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA-Protein interactions
Spatiotemporal-controlled second messengers alter molecular interactions of central signaling nodes for ensuring physiological signal transmission. One prototypical second messenger molecule which modulates kinase signal transmission is the cyclic-adenosine monophosphate (cAMP). The main proteinogen...
ORGANISM(S): Homo sapiens (Human) 
2024-04-04 | PXD048869 | Pride
Camp Taf15 Pka Phosphorylation Rna 
TranscriptomicsRNA-Seq profiling of C2C12 cells with exogenous expression of Mef2Da1 and Mef2Da2
Although splicing occurs in most multi-exon genes, the generation of distinct isoforms through the alternate use of mutually exclusive exons is less prevalent. As exon-switching events have the potential to give rise to isoforms with different cellular functions, we have explored the role of the mus...
ORGANISM(S): Mus musculus 
2013-06-03 | E-GEOD-46363 | biostudies-arrayexpress
UnknownPhosphorylation of the cAMP-dependent protein kinase (PKA) regulatory subunit modulates PKA-AKAP interaction, substrate phosphorylation, and calcium signaling in cardiac cells.
Not available
S-EPMC2527120 | biostudies-literature
TranscriptomicsTranscription profiling of mouse S49 lymphoma cell deathless (D-) cell variant
The second messenger cAMP acts via protein kinase A (PKA) to induce apoptosis by mechanisms that are poorly understood. Here, we assessed a role for mitochondria and analyzed gene expression in cAMP/PKA-promoted apoptosis by comparing wild-type (WT) S49 lymphoma cells and the S49 variant, D- (cAMP-d...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9727 | biostudies-arrayexpress
ProteomicsPRM of Nth1 phospho-peptides in response to AGC-kinase inhibition
Protein phosphorylation cascades play a central role in the regulation of cell growth and protein kinases PKA, Sch9 and Ypk1 take centre stage in regulating this process in S. cerevisiae. To understand how these kinases co-ordinately regulate cellular functions we compared the phospho-proteome of ex...
ORGANISM(S): Saccharomyces Cerevisiae 
2020-03-22 | PXD015760 | panorama
UnknownKChIP4a regulates Kv4.2 channel trafficking through PKA phosphorylation.
Not available
S-EPMC2823810 | biostudies-literature
ProteomicsSmoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) activates glioma-associated (GLI) transcription facto...
ORGANISM(S): Homo Sapiens 
2021-04-25 | PXD023893 | panorama
UnknownSystems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes.
Not available
S-EPMC1568947 | biostudies-literature
Sort   by:  
 Page size