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ProteomicsProteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation.
Follicles of polycystic ovaries (PCO) often become arrested in early antral stages at around 3 to 11 mm in diameter. The condition disturbs dominant follicle selection and may result in altered ovulation and anovulation. During the growth and development of human follicles, the follicular fluid (FF)...
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD031485 | Pride
Proteomics Oocyte maturation. Small antral follicles Follicular fluid 
ProteomicsProteomic Analysis Enables Distinction of Early- Versus Advanced-Stage Lung Adenocarcinomas
Background: A gel-free proteomic approach was utilized to perform in-depth tissue protein profiling of lung adenocarcinoma (ADC) and normal lung tissues from early and advanced stages of the disease. The long-term goal of this study is to generate a large-scale, label-free proteomic data set from hi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019259 | Pride
Adenocarcinoma Lung cancer Mass spectrometry Proteomics 
ProteomicsNovel potentially clinically valuable protein markers of androgen activity in humans
Background Testosterone (T) is the main androgen playing a crucial role in regulating the function of both reproductive and non-reproductive organs. Current methods for assessing T levels in humans do not reflect the biological androgenic activity (BAA), which may be important for example in the di...
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD024448 | Pride
Testosterone deficiency Proteomics Androgen activity Biomarkers 
ProteomicsProgressive Changes in Human Follicular Fluid Composition over the Course of Ovulation: Quantitative Proteomic Analyses.
The composition of follicular fluid reflects crucial paracrine signalling between granulosa- and theca cells and the oocyte. Dynamic changes in the protein composition of human follicular fluid across multiple time points in the period where final meiotic maturation and release of the oocyte take pl...
ORGANISM(S): Homo sapiens (Human) 
2019-07-29 | PXD012561 | Pride
Ovulation Human Oocyte maturation Follicular fluid Proteome 
ProteomicsProteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation.
Protein composition of human ovarian follicular fluid (FF) constitutes the microenvironment for oocyte development. Several proteomics studies of FF from pre-ovulatory follicles have revealed insights on oocyte maturation, however, there is a lack of knowledge on changes produced at protein levels i...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021338 | Pride
Proteomics Oocyte maturation. Small antral follicles Follicular fluid 
ProteomicsProteome of fluid from human small antral follicles reveals insights in folliculogenesis and oocyte maturation.
Human ovarian follicles develop a fluid-filled antrum when they reach a diameter of around 250 µm. The antrum contains follicular fluid (FF) composed of secretions from cells in the follicle and from circulation. The composition of FF undergoes massive changes in relation to follicular development. ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013344 | Pride
Follicles Proteomics Human Folliculogenesis Follicular fluid 
ProteomicsMicropillar-induced changes in cell nucleus morphology enhance bone regeneration by modulating the secretome
To investigate the influence of micropillars on proteomics, we seeded cells on flat and micropillar surfaces followed by (1) collection of proteins in cells on flat and micropillar surfaces; (2) collection of proteins secreted into medium by cells on flat and micropillar surfaces.
ORGANISM(S): Homo sapiens (Human) 
2025-05-19 | PXD059752 | Pride
Micropillar Secretome Modulation 
UnknownAcute-on-chronic liver failure (ACLF): the 'Kyoto Consensus'-steps from Asia.
Not available
S-EPMC11846769 | biostudies-literature
UnknownGlobal burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Not available
S-EPMC12535838 | biostudies-literature
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