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Follicles of polycystic ovaries (PCO) often become arrested in early antral stages at around 3 to 11 mm in diameter. The condition disturbs dominant follicle selection and may result in altered ovulation and anovulation. During the growth and development of human follicles, the follicular fluid (FF)...
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD031485 | Pride
Background: A gel-free proteomic approach was utilized to perform in-depth tissue protein profiling of lung adenocarcinoma (ADC) and normal lung tissues from early and advanced stages of the disease. The long-term goal of this study is to generate a large-scale, label-free proteomic data set from hi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019259 | Pride
Background Testosterone (T) is the main androgen playing a crucial role in regulating the function of both reproductive and non-reproductive organs. Current methods for assessing T levels in humans do not reflect the biological androgenic activity (BAA), which may be important for example in the di...
ORGANISM(S): Homo sapiens (Human) 
2022-04-07 | PXD024448 | Pride
The composition of follicular fluid reflects crucial paracrine signalling between granulosa- and theca cells and the oocyte. Dynamic changes in the protein composition of human follicular fluid across multiple time points in the period where final meiotic maturation and release of the oocyte take pl...
ORGANISM(S): Homo sapiens (Human) 
2019-07-29 | PXD012561 | Pride
Protein composition of human ovarian follicular fluid (FF) constitutes the microenvironment for oocyte development. Several proteomics studies of FF from pre-ovulatory follicles have revealed insights on oocyte maturation, however, there is a lack of knowledge on changes produced at protein levels i...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021338 | Pride
Human ovarian follicles develop a fluid-filled antrum when they reach a diameter of around 250 µm. The antrum contains follicular fluid (FF) composed of secretions from cells in the follicle and from circulation. The composition of FF undergoes massive changes in relation to follicular development. ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013344 | Pride
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