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TranscriptomicsTranscription profiling of human placenta isolated from first time mothers with placental malaria
Chronic inflammation during placental malaria (PM) caused by Plasmodium falciparum is most frequent in first-time mothers and is associated with poor maternal and fetal outcomes. In the first genome wide analysis of the local human response to sequestered malaria parasites, we identified genes assoc...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7586 | biostudies-arrayexpress
ProteomicsIntegrated proteomics reveals apoptosis-related mechanisms associated with past-chronic stage of placental malaria
Malaria in pregnancy remains a substantial public health concern in malaria-endemic areas. Accumulation of maternal immune cells in the placenta and increased levels of inflammatory cytokines caused by sequestration of Plasmodium falciparum-infected erythrocytes (IE) in the placental intervillous bl...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2018-09-25 | PXD008079 | Pride
Phosphoproteome Placental malaria Glycoproteome Proteome P. falciparum 
TranscriptomicsCharacterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5′ cap status
The mRNA 5′ cap is normally essential for eukaryotic mRNA translation, stabilization and transport and both the cap and eIF4E are important elements of post-transcriptional gene regulation. To further our understanding of mRNA translation in the human malaria parasite Plasmodium falciparum, we hav...
ORGANISM(S): Plasmodium falciparum 
2010-06-10 | E-GEOD-6356 | biostudies-arrayexpress
ProteomicsMolecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding
VAR2CSA is the placental-malaria specific member of the antigenically variant Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family. It is expressed on the surface of Plasmodium falciparum infected host red blood cells and binds to specific chondroitin-4-sulfate chains of the placenta...
ORGANISM(S): Homo sapiens (Human) 
2020-12-02 | PXD021873 | Pride
Lc-msms 
UnknownThe Effect of Intermittent Preventive Treatment of Malaria During Pregnancy and Placental Malaria on Infant Risk of Malaria.
Not available
S-EPMC8763957 | biostudies-literature
UnknownThe impact of gravidity, symptomatology and timing of infection on placental malaria.
Not available
S-EPMC7315526 | biostudies-literature
GenomicsPlacental Malaria Induces a Unique Methylation Profile Associated with Fetal Growth Restriction
Placental Malaria Induces a Unique Methylation Profile Associated with Fetal Growth Restriction
PRJNA1175699 | ENA
TranscriptomicsGenome wide analysis of placental malaria
Chronic inflammation during placental malaria (PM) caused by Plasmodium falciparum is most frequent in first-time mothers and is associated with poor maternal and fetal outcomes. In the first genome wide analysis of the local human response to sequestered malaria parasites, we identified genes assoc...
ORGANISM(S): Homo sapiens 
2007-07-01 | GSE7586 | GEO
UnknownDistinct placental malaria pathology caused by different Plasmodium berghei lines that fail to induce cerebral malaria in the C57BL/6 mouse.
Not available
S-EPMC3485172 | biostudies-literature
UnknownRelationships between infection with Plasmodium falciparum during pregnancy, measures of placental malaria, and adverse birth outcomes.
Not available
S-EPMC5629777 | biostudies-literature
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