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MetabolomicsThe glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity
The trade-off between growth and defense is a critical aspect of plant immunity. Therefore, the plant immune response needs to be tightly regulated. Salicylic acid (SA) is an important plant hormone regulating defense against biotrophic pathogens. Recently, N-hydroxy-pipecolic acid (NHP) was identif...
2022-02-28 | MTBLS2334 | MetaboLights
TranscriptomicsPreadaptation of Yersinia pestis to resist mammalian innate immunity during transit through the flea vector
Yersinia pestis, the agent of plague, is transmitted to mammals by infected fleas. Y. pestis exhibits a distinct life stage in the flea, where it grows in the form of a cohesive biofilm that promotes transmission. After transmission, the temperature shift to 37°C induces many known virulence factors...
ORGANISM(S): Yersinia pestis 
2010-04-06 | E-GEOD-16493 | biostudies-arrayexpress
TranscriptomicsHuman keratinocytes have a response to injury that upregulates CCL20 and other genes linking innate and adaptive immunity
In the early stages of wound healing, keratinocytes become “activated” and release inflammatory molecules such as interleukin-1 and interleukin-8 that are linked to innate immune responses and neutrophil recruitment. It is unclear, however, whether keratinocytes release molecules linked to adaptive ...
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-30355 | biostudies-arrayexpress
UnknownThe major leaf ferredoxin Fd2 regulates plant innate immunity in Arabidopsis.
Not available
S-EPMC6637997 | biostudies-literature
TranscriptomicsExpression analysis of Arabidopsis transgenic plants carrying DEX-inducible MKK4DD in Col or sid2 background treated with DEX or control
Effector-Triggered Immunity (ETI) and Pattern-Triggered Immunity (PTI) are well-defined modes of plant immunity triggered by recognition of pathogen effector proteins and microbe-associated molecular patterns, respectively. While ETI and PTI network extensively share signaling components, the shared...
ORGANISM(S): Arabidopsis thaliana 
2014-07-29 | E-GEOD-40547 | biostudies-arrayexpress
TranscriptomicsExpression analysis of Arabidopsis plants infected with Pseudomonas syringae pv. tomato DC3000 (Pto) strains
Effector-Triggered Immunity (ETI) and Pattern-Triggered Immunity (PTI) are well-defined modes of plant immunity triggered by recognition of pathogen effector proteins and microbe-associated molecular patterns, respectively. While ETI and PTI network extensively share signaling components, the shared...
ORGANISM(S): Arabidopsis thaliana 
2014-07-29 | E-GEOD-40544 | biostudies-arrayexpress
UnknownPlant innate immunity--sunny side up?
Not available
S-EPMC4817832 | biostudies-literature
TranscriptomicsIdentification of early flg22 responsive genes in Arabidopsis seedlings
The goal of this experiment was to identify the early responsive genes activated by the 22 amino acid peptide of bacterial flagellin (flg22) in Arabidopsis seedlings that are involved in the initial responses important for plant innate immunity. We used the microarrays to detail the global program o...
ORGANISM(S): Arabidopsis thaliana 
2010-03-18 | E-GEOD-17382 | biostudies-arrayexpress
TranscriptomicsMacrophage-specific gene functions in Spi1-directed innate immunity
The Spi1/ Pu.1 transcription factor plays a crucial role in myeloid cell development across many species. Several Spi1 target genes have been identified so far, yet the Spi1-dependent gene group remains largely unknown. To identify novel genes downstream of Spi1 we employed a microarray strategy usi...
ORGANISM(S): Danio rerio 
2010-04-30 | E-GEOD-19206 | biostudies-arrayexpress
ProteomicsTwo-layer response sensitisation and actuation establishes signal waves for systemic innate immunity
Intercellular and systemic signalling is an essential hallmark of multicellular life. Encounter of pathogens occurs locally but triggers organ scale and organismic immune responses. In plants, elicitor perception provokes rapid, systemically expanding Ca2+ and H2O2 second messenger signals conferrin...
ORGANISM(S): Homo Sapiens (human) 
2024-11-28 | PXD038633 | JPOST Repository
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