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MetabolomicsMetabolomic determinants of carotid atherosclerosis plaque stability
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
2025-06-06 | MTBLS12303 | MetaboLights
TranscriptomicsMulti-platform approach for plaque-derived biomarkers for the vulnerable plaque. Challenges and promises.
Plaque rupture and subsequent thrombus formation is responsible for the majority of clinical complications of atherosclerosis and nonetheless our understanding of what underlies plaque vulnerability and rupture is still sparse and mostly deductively based on animal models and in vitro studies. We ad...
ORGANISM(S): Homo sapiens 
2014-05-17 | E-MTAB-2055 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of human atherosclerotic plaque: Carotid plaque
In order to identify potential new biomarkers of atherosclerotic plaque composition we performed a large scale analysis of gene expression patterns in human atherosclerotic lesions. Whole genome expression analysis of 101 peripheral plaques identified a robust gene signature (1514 genes) dominated ...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-24495 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of human atherosclerotic plaque: 101 peripheral plaques
In order to identify potential new biomarkers of atherosclerotic plaque composition we performed a large scale analysis of gene expression patterns in human atherosclerotic lesions. Whole genome expression analysis of 101 peripheral plaques identified a robust gene signature (1514 genes) dominated ...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-23304 | biostudies-arrayexpress
UnknownProtruding Aortic Plaque and Coronary Plaque Vulnerability.
Not available
S-EPMC10926811 | biostudies-literature
TranscriptomicsGene expression profiling of human atherosclerotic plaque: Laser capture microscopy of smooth muscle cells and macrophages
In order to identify potential new biomarkers of atherosclerotic plaque composition we performed a large scale analysis of gene expression patterns in human atherosclerotic lesions. Whole genome expression analysis of 101 peripheral plaques identified a robust gene signature (1514 genes) dominated ...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-23303 | biostudies-arrayexpress
UnknownRole of oncostatin-M in ECM remodeling and plaque vulnerability.
Not available
S-EPMC10579161 | biostudies-literature
UnknownAssociation between plaque vulnerability and neutrophil extracellular traps (NETs) levels: The Plaque At RISK study.
Not available
S-EPMC9182254 | biostudies-literature
GenomicsAccelerated RNA polymerase II elongation drives endothelial transition and plaque vulnerability: pharmacological targeting of the super elongation complex [RNA-seq]
Accelerated RNA polymerase II elongation drives endothelial transition and plaque vulnerability: pharmacological targeting of the super elongation complex [RNA-seq]
PRJNA1463192 | ENA
GenomicsAccelerated RNA polymerase II elongation drives endothelial transition and plaque vulnerability: pharmacological targeting of the super elongation complex [ChIP-seq]
Accelerated RNA polymerase II elongation drives endothelial transition and plaque vulnerability: pharmacological targeting of the super elongation complex [ChIP-seq]
PRJNA1463152 | ENA
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