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ProteomicsPlasma ALS and LG3BP predict liver fibrosis in NAFLD patients
Non-alcoholic fatty liver disease (NAFLD) is estimated to affect 25% of the world’s population and its prevalence is increasing with the rise in obesity. The evolution of this disease includes different pathological stages: steatosis, inflammation, fibrosis, cirrhosis and hepatocellular carcinoma (H...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD043340 | Pride
Plasma nafld biomarkers discovery 
ProteomicsPlasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) affects 25% of the population and can progress to cirrhosis, where treatment options are limited. As the liver secrets most of the blood plasma proteins, its diseases should affect the plasma proteome. Plasma Proteome Profiling of 48 patients with cirrhosis ...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-05 | PXD012056 | Pride
Mass spectrometry Biomarker discovery Plasma proteome profiling Nafld Nash 
ProteomicsIntegrated liver and plasma proteomics in obese mice reveals complex metabolic and immune regulation
Obesity leads to the development of non-alcoholic fatty liver disease (NAFLD) and associated alterations to the plasma proteome. To elucidate the underlying changes associated with obesity, we performed liquid chromatography-tandem mass spectrometry in the liver and plasma of obese leptin-deficient ...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-01 | PXD026821 | Pride
Proteome Ob/ob Obesity Lcms Nafld 
UnknownBiomarker Discovery in Liver Disease Using Untargeted Metabolomics in Plasma and Saliva.
Not available
S-EPMC11432510 | biostudies-literature
UnknownAdiposity, metabolomic biomarkers, and risk of nonalcoholic fatty liver disease: a case-cohort study.
Not available
S-EPMC8895224 | biostudies-literature
TranscriptomicsStellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity
Non-alcoholic fatty liver disease (NAFLD) and its progressive form, non-alcoholic steatohepatitis (NASH), are the hepatic manifestations of metabolic syndrome. Histological assessment of liver biopsies is the gold standard for diagnosis of NASH. A Liver biopsy is resource heavy and can lead to compl...
ORGANISM(S): Homo sapiens 
2022-11-02 | GSE207310 | GEO
UnknownBeneficial Effects of Dietary Flaxseed on Non-Alcoholic Fatty Liver Disease.
Not available
S-EPMC10892801 | biostudies-literature
GenomicsStellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity
Stellate cell expression of SPARC-related modular calcium-binding protein 2 is associated with human non-alcoholic fatty liver disease severity
PRJNA854662 | ENA
UnknownUntargeted Profiling of Bile Acids and Lysophospholipids Identifies the Lipid Signature Associated with Glycemic Outcome in an Obese Non-Diabetic Clinical Cohort.
Not available
S-EPMC7407211 | biostudies-literature
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