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TranscriptomicsL-plastin Ser5 phosphorylation via RSKs, downstream effectors of the MAPK/ERK pathway, in (breast) cancer cells (and in vitro)
Deregulated cell migration and invasion, which are hallmarks of metastatic cancer cells, are correlated to structural and functional alterations of the actin cytoskeleton associated to a large panel of actin-binding proteins. Among these, the actin-bundling protein L-plastin, initially detected in l...
ORGANISM(S): Homo sapiens 
2016-03-26 | E-MTAB-3487 | biostudies-arrayexpress
GenomicsPlastin 3 rescues deficient TrkB/BDNF signaling and protects from dysregulations in Ca2+ homeostasis in SMA mouse models
Plastin 3 rescues deficient TrkB/BDNF signaling and protects from dysregulations in Ca2+ homeostasis in SMA mouse models
PRJNA811425 | ENA
UnknownThe Calcium-Dependent Switch Helix of L-Plastin Regulates Actin Bundling.
Not available
S-EPMC5286426 | biostudies-literature
UnknownExosomal Release of L-Plastin by Breast Cancer Cells Facilitates Metastatic Bone Osteolysis.
Not available
S-EPMC6305809 | biostudies-literature
UnknownmiR-375 Regulates Invasion-Related Proteins Vimentin and L-Plastin.
Not available
S-EPMC5500828 | biostudies-literature
UnknownFascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia.
Not available
S-EPMC4861481 | biostudies-literature
UnknownStructural mechanism for bidirectional actin cross-linking by T-plastin.
Not available
S-EPMC9478642 | biostudies-literature
UnknownNeutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis.
Not available
S-EPMC7147296 | biostudies-literature
TranscriptomicsPlastin 3 rescues deficient TrkB/BDNF signaling and protects from dysregulations in Ca2+ homeostasis in SMA mouse models
Spinal muscular atrophy (SMA) is a lethal pediatric neuromuscular disease caused by loss of the Survival Motor Neuron 1 gene (SMN1). Although current therapies focus very efficiently on SMN restoration, the cellular mechanisms underlying the pathological features are not fully understood. Smn-defici...
ORGANISM(S): Mus musculus 
2023-01-05 | GSE197638 | GEO
UnknownL-Plastin Phosphorylation: Possible Regulation by a TNFR1 Signaling Cascade in Osteoclasts.
Not available
S-EPMC8464874 | biostudies-literature
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