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Leukocyte-platelet rich fibrin (L-PRF) is extensively used in the dentistry field and other clinical scenarios due to its regeneration properties. We obtained L-PRF membranes in absence of anticoagulants and cultured in DMEM. The secretomewas collected at days 3, 7 and 21 in order to identify the pr...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD017963 | Pride
Considering that PRF is clinically used in combination with dental implants and collagen membranes, we exposed titanium discs and collagen membranes to PRF lysates. We showed here that PRF-derived TGF-β activity adsorbs to titanium implants and collagen membranes indicated by the changes in gene exp...
ORGANISM(S): Homo sapiens (Human) 
2020-06-24 | PXD014382 | Pride
Results: MiRNA expression profiling of 1281 human miRNAs revealed relevant expression of 221 miRNAs consistently expressed in all samples at all time points. Correlation of platelet miRNA ranks was highly significant with data from other studies. Global distribution of miRNA expression was relativel...
ORGANISM(S): Homo sapiens 
Platelet-rich fibrin induces an inflammatory phenotype of U937 macrophages
Platelet-Rich Fibrin Potentiates Dental Pulp Stem Cell Angiogenesis through Mitochondrial Transfer-Meditated Metabolic-Signaling Integration
The objective of the present study was to compare the secretome of BMSC (BMSC-CM) to that of L-PRF (LPRF-CM) – an established standard for GF therapy, in the context of wound healing and regeneration.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041617 | Pride
RNAseq of peripheral blood mononucleated cells exposed to platelet-rich fibrin and enamel matrix derivatives.
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