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Sinorhizobium meliloti is a soil-dwelling symbiotic alphaproteobacterium. Cyclic di-GMP is an important second messenger controlling multiple functions in this microorganism. To understand transcriptional regulation by elevated c-di-GMP in S. meliloti, the transcriptome analysis was performed on the...
ORGANISM(S): Sinorhizobium meliloti 
In order to know the effect of the second messenger cyclic di-GMP (cdGMP) on the global transcription of A. baumannii AB0057, we performed a differential RNA sequencing (dRNA-seq) experiment comparing two AB0057 derivatives that allow IPTG-induced overexpression of the phosphodiesterase coding gene ...
ORGANISM(S): Acinetobacter baumannii AB0057 
2026-03-19 | GSE291750 | GEO
In order to know the effect of the second messenger cyclic di-GMP (cdGMP) on the global transcription of A. baumannii AB5075, we performed a differential RNA sequencing (dRNA-seq) experiment comparing two AB5075 derivatives that allow IPTG-induced overexpression of the phosphodiesterase coding gene ...
ORGANISM(S): Acinetobacter baumannii AB5075 
2026-03-19 | GSE229819 | GEO
In the model organism Caulobacter crescentus, a network of two-component systems involving the response regulators CtrA, DivK and PleD coordinate cell cycle progression with differentiation. Active phosphorylated CtrA prevents chromosome replication in G1 cells while simultaneously regulating expres...
ORGANISM(S): Caulobacter vibrioides 
2020-06-09 | GSE152025 | GEO
Global transcription changes driven by the second messenger cyclic di-GMP in Acinetobacter baumannii AB5075
Global transcription changes driven by the second messenger cyclic di-GMP in Acinetobacter baumannii AB0057
Regulation of bacterial cell cycle progression by redundant phosphatases
To analyze the impact of elevated c-di-GMP concentrations in P. aeruginosa, we expressed pleD* on an inducible vector (pHERD20T) in the PAO1 wild-type strain. PleD is a DGC from Caulobacter cresentusand the pleD* construct variant encodes for a constitutively active enzyme due to four amino acid exc...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2022-07-25 | PXD027098 | Pride
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