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ProteomicsProteomic analysis of pleomorphic dermal sarcoma
In this study, we aimed to unravel the molecular underpinnings of pleomorphic dermal sarcomas (PDS), rare skin tumors often seen in sun-exposed regions. Using mass spectrometry, we examined proteomic profiles of 20 samples of normal healthy skin tissue (SNT), 27 malignant melanomas (MM), 20 cutaneou...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD046388 | Pride
Immune evasion Protein analysis Fibroblastic lineage Pleomorphic dermal sarcoma (pds) 
TranscriptomicsSingle-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma
Undifferentiated pleomorphic sarcoma (UPS) and related tumors are the most common type of soft tissue sarcoma. However, this spectrum of tumors has different etiologies with varying rates of metastasis and survival. Two dermal-based neoplasms in this class of pleomorphic sarcomas, atypical fibroxant...
ORGANISM(S): Homo sapiens 
2024-11-10 | GSE281529 | GEO
TranscriptomicsSingle-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma [scRNA-Seq]
Undifferentiated pleomorphic sarcoma (UPS) and related tumors are the most common type of soft tissue sarcoma. However, this spectrum of tumors has different etiologies with varying rates of metastasis and survival. Two dermal-based neoplasms in this class of pleomorphic sarcomas, atypical fibroxant...
ORGANISM(S): Homo sapiens 
2024-11-08 | GSE281096 | GEO
GenomicsSingle-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma
Single-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma
PRJNA1184336 | ENA
UnknownSingle-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma.
Not available
S-EPMC11566467 | biostudies-literature
UnknownMYC gene amplification is a rare event in atypical fibroxanthoma and pleomorphic dermal sarcoma.
Not available
S-EPMC5940384 | biostudies-literature
UnknownProteomic analysis of pleomorphic dermal sarcoma reveals a fibroblastic cell of origin and distinct immune evasion mechanisms.
Not available
S-EPMC11143252 | biostudies-literature
GenomicsSingle-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma [scRNA-Seq]
Single-cell and spatial transcriptomics identify COL6A3 as a prognostic biomarker in undifferentiated pleomorphic sarcoma [scRNA-Seq]
PRJNA1182275 | ENA
UnknownClinicopathological and Genomic Profiles of Atypical Fibroxanthoma and Pleomorphic Dermal Sarcoma Identify Overlapping Signatures with a High Mutational Burden.
Not available
S-EPMC8303615 | biostudies-literature
UnknownRisk factors for local atypical fibroxanthoma recurrence and progression to pleomorphic dermal sarcoma: A meta-analysis of individualized participant data.
Not available
S-EPMC9544245 | biostudies-literature
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