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ProteomicsPleural fluid proteomics from patients with pleural infection shows signatures of diverse neutrophilic responses: The Oxford Pleural Infection Endotyping Study (TORPIDS 2)
Pleural infection is a severe and complicated disease with increasing incidence worldwide and is characterised by substantial associated morbidity and mortality.1,2 Although it is accepted that the disease is heterogeneous, and there is a validated clinical prediction score (RAPID)3,4, the biologica...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD054108 | Pride
Bacteriology Empyema Pleural infection Microbiology Pleural fluid 
TranscriptomicsHuman fetal chylothorax: pleural fluid vs. ascites fluid
Transcriptional profile comparison of the pleural and ascites fluids in hydropic fetuses affected with chylothorax. Two-condition experiment, pleural fluid vs. ascites fluid. Comparison of the transcriptional profile between sample collected before and after OK-432 treatment and between fetuses with...
ORGANISM(S): Homo sapiens 
2012-12-31 | E-GEOD-33872 | biostudies-arrayexpress
ProteomicsMapping the soluble human leukocyte antigen peptidome of pleural effusions reveals lung and tumor-associated antigens
Soluble HLA (sHLA) molecules released to the plasma, carry their original peptide cargo and provide insight into the protein synthesis and degradation schemes of their source cells and tissues. Other body fluids, such as pleural effusions, may also contain sHLA-peptide complexes, and can potentially...
ORGANISM(S): Homo sapiens (Human) 
2022-05-25 | PXD027766 | Pride
Tumor antigens Immunopeptisome Pleural effusion Cancer/testis antigens Hla peptidome Lung cancer Lc-ms/ms 
UnknownIncidence of Discordant Pleural Fluid Exudates and Diagnostic Patterns: A Retrospective Cohort Study.
Not available
S-EPMC12833483 | biostudies-literature
GenomicsHeart Failure Pleural Fluid Impairs Endothelial Barrier through miR 501-3p Mediated ZO 1 Remodeling
Heart Failure Pleural Fluid Impairs Endothelial Barrier through miR 501-3p Mediated ZO 1 Remodeling
PRJNA1425950 | ENA
UnknownIdentifying Thoracic Malignancies Through Pleural Fluid Biomarkers: A Predictive Multivariate Model.
Not available
S-EPMC4998909 | biostudies-literature
TranscriptomicsHeart Failure Pleural Fluid Impairs Endothelial Barrier through miR 501-3p Mediated ZO 1 Remodeling
Summary: Heart failure is frequently accompanied by pleural effusion, yet the biological impact of heart failure–associated pleural fluid on vascular endothelial function remains unclear. Here, we show that heart failure pleural fluid impairs endothelial barrier integrity and angiogenic capacity in ...
ORGANISM(S): Homo sapiens 
2026-03-12 | GSE319996 | GEO
UnknownPleural fluid carbohydrate antigen 72-4 and malignant pleural effusion: a diagnostic test accuracy study.
Not available
S-EPMC10775747 | biostudies-literature
GenomicsThe microbiology of pleural infection
The bacteriology of pleural infection using next generation sequencing: The Oxford Pleural Infection Metagenomics Studies (TORPIDS)
PRJEB40449 | ENA
ProteomicsUnbiased undepleted malignant pleural effusion proteomics study
Pleural effusion (PE) occurs as a consequence of various pathologies. Malignant effusion due to lung cancer is one of the most frequent causes. Methods for accurate differentiation of malignant from benign PE cases are an unmet clinical need. Proteomics profiling of PE has shown promising results. H...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD035884 | Pride
Pleural effusion Real life clinical cohort Human Biomarker Malignant 
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