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ProteomicsRNA degradosome components purified from Mycobacterium tuberculosis
The dataset accompanying a publication describing the RNA degradosome components in Mycobacterium tuberculosis (Mtb). Individual RNA degradosome components from Mtb (PNPase, RNase E, RNase J, RhlE and Enolase) were tagged with eGFP and used as baits to pull-down their interaction partners. The prote...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2019-04-01 | PXD012662 | Pride
Tuberculosis Rna degradation 
ProteomicsRNA-bound proteome of Mycobacterium bovis
The dataset accompanying a publication describing the RNA degradosome components in Mycobacterium tuberculosis (Mtb). The RNA-bound proteome was determined by affinity purification of protein-RNA complexes from Mycobacterium bovis cells fed with 4-thiouridine and crosslinked via photoactivation at 3...
ORGANISM(S): Mycobacterium bovis 
2019-04-01 | PXD012661 | Pride
Tuberculosis Rna degradosome Rna bound proteome 
ProteomicsProteome of Mycobacterium tuberculosis treated with 2,4-disubstituted pyridine derivatives
Two selected compounds, 2,4-disubstituted pyridine derivatives (11 and 15), revealed significant bactericidal activity against Mycobacterium tuberculosis deposited within human macrophages as well as against biofilm-forming tubercle bacilli. The mass spectrometry-based proteomics (LC-MS/MS) of the w...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2022-11-02 | PXD035807 | Pride
Mycobacterium tuberculosis Antimicrobials 
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