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TranscriptomicsTranscription profiling of human U927 cells polysomal and cytoplasmic RNA before and after PMA stimulation
Human histomonocytic U937 cells exhibit macrophage-like properties after phorbol ester stimulation. Accumulating evidence demonstrated that remarkable number of transcripts changed in their amount at total RNA levels. However, post-transcriptional regulation has not been fully elucidated in this m...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1783 | biostudies-arrayexpress
TranscriptomicsExpression data from knockdown of ZXDC1/2 in PMA-treated U937
ZXDC1 augments the expression of various markers of monocyte/macrophage differentiation when over-expressed in the U937 cell line treated with the phorbol ester PMA. Likewise, knockdown of ZXDC1 restricts the induced expression of these markers. We sought to identify specfic gene targets of ZXDC1 ...
ORGANISM(S): Homo sapiens 
2013-10-01 | E-GEOD-45417 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in human THP-1 cell line undifferentiated, 3 days or 8 days differentiated with phorbol myristate acetate (PMA)
We analysed the capacity of THP-1 cells (differentiated to macrophagoid cells) to recognize RNA sequences via pattern recognition receptors in vitro. Gene expression was analysed by RNA-Microarray. Cytokine production was analysed by ELISA assays. We used microarrays to investigate differential gen...
ORGANISM(S): Homo sapiens 
2015-11-09 | E-GEOD-67264 | biostudies-arrayexpress
TranscriptomicsProfiling of Jurkat T cells activated with CD3, CD28 and PMA at 1 and 8 hours
T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype, depending on environmental co-stimulatory signals. In order to identify the genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes ...
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-30676 | biostudies-arrayexpress
UnknownProtocol for PMA-Ethiopia: A new data source for cross-sectional and longitudinal data of reproductive, maternal, and newborn health.
Not available
S-EPMC7593701 | biostudies-literature
TranscriptomicsTranscriptomics analysis of LPS-induced changes in PMA-differentiated human THP-1 cells
RNA-Seq was carried out in order to obtain the expression profile of lipopolysaccharide (LPS)-induced transcriptome changes in PMA-differentiated human THP-1 cell line.
ORGANISM(S): Homo sapiens 
2021-10-17 | E-MTAB-10513 | biostudies-arrayexpress
TranscriptomicsImpact of HP1gamma and HP1gamma S83 phosphorylation on the transcriptionnal effect of PMA stimulation of mouse fibroblasts
We have here followed the transcriptional effect of stimulation with the phorbol ester PMA in mouse fibroblasts from HP1gamma null mice recomplemented with either wild-type HP1gamma or an HP1g with an S83A mutation Spontaneously immortalized mouse embryonic fibroblasts from HP1gamma null mice were u...
ORGANISM(S): Mus musculus 
2014-11-01 | E-GEOD-60283 | biostudies-arrayexpress
Genomics1,25-dihydroxyvitamin D3 augments low-dose PMA-based monocyte-to-macrophage differentiation in THP-1 cells
PMA- and PMA with 1,25D3-differentiated THP-1 cells
PRJEB76891 | ENA
GenomicsTHP-1 cells PMA-treated RNA-seq
THP-1 cells PMA-treated RNA-seq
PRJNA632845 | ENA
TranscriptomicsExpression profiling of myeloid leukemia cell treated with vibsanine A, PMA and ATRA
All-trans retinoic acid (ATRA)-based differentiation therapy has achieved success with the treatment of acute promyelocytic leukemia (APL), a unique subtype of acute myeloid leukemia (AML). However, other subtypes of AML display resistance to ATRA-based treatment. Here, we demonstrate that a novel n...
ORGANISM(S): Homo sapiens 
2016-02-28 | E-GEOD-78734 | biostudies-arrayexpress
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