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TranscriptomicsTranscription profiling of human U927 cells polysomal and cytoplasmic RNA before and after PMA stimulation
Human histomonocytic U937 cells exhibit macrophage-like properties after phorbol ester stimulation. Accumulating evidence demonstrated that remarkable number of transcripts changed in their amount at total RNA levels. However, post-transcriptional regulation has not been fully elucidated in this m...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1783 | biostudies-arrayexpress
TranscriptomicsImpact of HP1gamma and HP1gamma S83 phosphorylation on the transcriptionnal effect of PMA stimulation of mouse fibroblasts
We have here followed the transcriptional effect of stimulation with the phorbol ester PMA in mouse fibroblasts from HP1gamma null mice recomplemented with either wild-type HP1gamma or an HP1g with an S83A mutation Spontaneously immortalized mouse embryonic fibroblasts from HP1gamma null mice were u...
ORGANISM(S): Mus musculus 
2014-11-01 | E-GEOD-60283 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of porcine PMBCs after stimulation by LPS or PMA/ionomycin using SLA-RI/NRSP8-13K chip
Background: During the past 25 years, selection of production traits highly increased pig production but diseases have emerged that may cause economic loss of extreme importance. Designing sustainable animal production that better balances productivity with resistance to disease is a major concern a...
ORGANISM(S): Sus scrofa 
2010-01-30 | E-GEOD-17320 | biostudies-arrayexpress
TranscriptomicsPolysomal and Cytoplasmic RNA of U937 cells before and after PMA stimulation
Human histomonocytic U937 cells exhibit macrophage-like properties after phorbol ester stimulation. Accumulating evidence demonstrated that remarkable number of transcripts changed in their amount at total RNA levels. However, post-transcriptional regulation has not been fully elucidated in this mod...
ORGANISM(S): Homo sapiens 
2004-11-01 | GSE1783 | GEO
TranscriptomicsProfiling of Jurkat T cells activated with CD3, CD28 and PMA at 1 and 8 hours
T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype, depending on environmental co-stimulatory signals. In order to identify the genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes ...
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-30676 | biostudies-arrayexpress
TranscriptomicsJurkat T cell gene expression with IKKe gene knockdown and PMA and ionomycin stimulation
We used microarray to monitor the differentially expresed genes during Jurkat T cell activaiton. Jurkat T cells with control shRNA or IKKe shRNA were treated with solvent or PMA and ionomycin for 3 h, and then RNA was extracted and applied to microarray analysis
ORGANISM(S): Homo sapiens 
2016-03-11 | E-GEOD-79074 | biostudies-arrayexpress
TranscriptomicsGenome-wide immunity studies in the rabbit: transcriptome variations in PBMCs after in vitro stimulation by LPS or PMA/ionomycin
Background: Our purpose was to obtain non-existing genome-wide expression data for the rabbit species on the responses of peripheral blood mononuclear cells (PBMCs) after in vitro stimulation by lipopolysaccharide (LPS) or phorbol myristate acetate (PMA) and ionomycin. This transcriptomic study was ...
ORGANISM(S): Oryctolagus cuniculus 
2014-07-10 | E-GEOD-59263 | biostudies-arrayexpress
TranscriptomicsProfiling of Jurkat T cells activated with CD3, CD28 and PMA and multiple kinase inhibitors
T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype, depending on environmental co-stimulatory signals. In order to identify the genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes ...
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-30674 | biostudies-arrayexpress
GenomicsRXR binding pattern in human PMA-differentiated THP-1 cells upon ligand stimulation [ChIP-seq]
RXR binding pattern in human PMA-differentiated THP-1 cells upon ligand stimulation [ChIP-seq]
PRJNA1398274 | ENA
GenomicsRXR binding pattern in human PMA-differentiated THP-1 cells upon ligand stimulation [RNA-seq]
RXR binding pattern in human PMA-differentiated THP-1 cells upon ligand stimulation [RNA-seq]
PRJNA1398279 | ENA
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