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TranscriptomicsPancreatic cancer organoid
Organoids from KPC pancreatic tumor tissue was treated with growth medium or conditional medium of mast cells treated with WT or BAG6 KO EVS of Pan02.
ORGANISM(S): Mus musculus 
2024-12-31 | E-MTAB-13570 | biostudies-arrayexpress
TranscriptomicsscRNAseq of tumor and blood of mice infected with Pan02 cells, WT and BAG6 deletion
Mice were infected with the pancreatic cancer cell line Pan02 (into their pancreas). 30 days later, pancreas was extracted, cells digested and BD Rhapsody RNAseq targeted against the MM immune panel was performed.
ORGANISM(S): Mus musculus 
2024-12-30 | E-MTAB-13573 | biostudies-arrayexpress
ProteomicsExtracellular vesicles from pancreatic cancer cells activate mast cells which in turn promote tumor cell proliferation and establish a tumor-supportive microenvironment
Background and aim: Recent studies reveal a critical role of tumor cell-released extracellular vesicles (EVs) in pancreatic cancer progression. Driver genes directing EV function, the EV-recipient cells, as well as their cellular response to EV uptake remain, however, to be identified. To address th...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-12-06 | MSV000093583 | MassIVE
TranscriptomicsBAG6KO impacts extracellular vesicle mRNA cargo
The mRNA cargo of B-16V and B-16V-delta-BAG6 cells was sequenced with RNA seq.
ORGANISM(S): Mus musculus 
2019-11-29 | E-MTAB-7123 | biostudies-arrayexpress
ProteomicsEffect of menstrual blood-derived mesenchymal stromal cell secretomes on macrophage polarization: therapeutic insights
Menstrual blood-derived mesenchymal stromal cells (MenSCs) are a promising alternative source of MSCs for clinical applications due to their unique advantages, including easy isolation and high proliferative capacity. They possess immunomodulatory and regenerative capabilities, interacting with immu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-01-22 | MSV000096909 | MassIVE
ProteomicsExtracellular vesicles derived from tumor-associated macrophages reveal unique contributions to the ovarian cancer microenvironment
Tumor progression and metastasis are promoted by ascites which constitutes a central part of the ovarian cancer (OC) tumor microenvironment (TME). One prominent immune cell type in ascites is represented by tumor-associated macrophages (TAMs) which contribute to tumor progression. Among other cells,...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-06-25 | MSV000098313 | MassIVE
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