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TranscriptomicsRelationship between nucleosome positioning and DNA methylation: ChIP-chip
Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of approximately 147 bases of DNA wrapped around a histone octamer1, 2. Here we report a genome-wide nucleosome positioning analysis of Arabidopsis thaliana utilizing massively parallel sequencing of mononucleosomes. By...
ORGANISM(S): Arabidopsis thaliana 
2010-05-28 | E-GEOD-21818 | biostudies-arrayexpress
GenomicsNELF-dependent transcription activation
Jurkat T-cells were latently infected with a defective HIV provirus carrying a GFP reporer gene. The cells were superinfected with a lentiviral vector expressing shRNA to NELF-E. The impact of NELF-depletion on RNAP II distribution on cellular genes and the HIV provirus was measured by ChIP-Seq. D...
ORGANISM(S): Homo sapiens 
2014-03-26 | E-GEOD-47481 | biostudies-arrayexpress
GenomicsRelationship between nucleosome positioning and DNA methylation: Bisulfite-Seq, ChIP-Seq, and Mnase-Seq
Nucleosomes compact and regulate access to DNA in the nucleus, and are composed of approximately 147 bases of DNA wrapped around a histone octamer. Here we report a genome-wide nucleosome positioning analysis of Arabidopsis thaliana utilizing massively parallel sequencing of mononucleosomes. By com...
ORGANISM(S): Homo sapiens 
2010-05-29 | E-GEOD-21821 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human malignant pleural mesothelioma tumors and cell lines
Malignant pleural mesothelioma (MPM) is a highly lethal, poorly understood neoplasm that is typically associated with asbestos exposure. We performed transcriptional profiling using high-density oligonucleotide microarrays containing approximately 22,000 genes to elucidate potential molecular and pa...
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2549 | biostudies-arrayexpress
UnknownAnalytical antiretroviral therapy interruption does not irreversibly change preinterruption levels of cellular HIV.
Not available
S-EPMC6289896 | biostudies-literature
UnknownA Mechanism for the Activation of the Influenza Virus Transcriptase.
Not available
S-EPMC6024077 | biostudies-literature
TranscriptomicsMyeloid Derived Suppressor Cells and Cancer
Transcriptional profiling of FACS-sorted and splenic control mouse cells, comparing splenic cells from FVBneuN vs Neu+ expressing FVBneuN mice with Gr1+ CD11b+ sorted tumor-infiltrating mononuclear or splenic myeloid-derived suppressor cells 4 groups or conditions. Biological replicates: 2 or 3 per ...
ORGANISM(S): Mus musculus 
2010-12-29 | E-GEOD-26289 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of non-obese diabetic (NOD) mice with or without the scid mutation and BDC2.5 TCR gene knock-in to study T-cell mediated B-cell damage and repair
Dynamic interaction between T-cell mediated beta-cell damage and beta-cell repair in the run up to autoimmune diabetes of the NOD mice.
ORGANISM(S): Mus musculus 
2006-10-03 | E-CBIL-18 | biostudies-arrayexpress
TranscriptomicsArabidopsis defense against Botrytis cinerea: chronology and regulation deciphered by high-resolution temporal transcriptomic analysis
This SuperSeries is composed of the following subset Series: GSE29642: Arabidopsis defense against Botrytis cinerea: chronology and regulation deciphered by high-resolution temporal transcriptomic analysis (time series) GSE39597: Arabidopsis defense against Botrytis cinerea: chronology and regulatio...
ORGANISM(S): Arabidopsis thaliana 
2012-10-03 | E-GEOD-39598 | biostudies-arrayexpress
GenomicsHistone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma [ChIP-seq]
Here we report a novel role for H2A.Z.2 (H2AFV) as a mediator of cell proliferation and sensitivity to targeted therapies in malignant melanoma. While both H2A.Z.1 and H2A.Z.2 are highly expressed in metastatic melanoma and correlate with decreased patient survival, only H2A.Z.2 deficiency results i...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-68223 | biostudies-arrayexpress
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