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Transcriptomicsmid-L2_polA_enriched_20dC_14hrs_post-L1_N2_tiling_array
modENCODE_submission_477 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23266 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of six mammals
Homologous vertebrate tissues express a highly conserved set of transcribed genes; paradoxically, expression of tRNAs that are required to translate mRNAs into proteins have been reported to be divergent. To resolve this paradox, we mapped the genome-wide occupancy of pol III in primary tissues iso...
ORGANISM(S): Mus musculus 
2011-07-29 | E-MTAB-424 | biostudies-arrayexpress
TranscriptomicsHypothalamic gene expression in small litter vs control mouse (postnatal overnutrition)
Gene expression microarray profiling in adult (P180) small litter vs control mice. Total RNA isolated from hypothalamus excised from P180 males and females; 3 mice in each sex and each group (12 total).
ORGANISM(S): Mus musculus 
2012-10-01 | E-GEOD-40616 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast timecourse mcs6 mutant
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-192 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast timecourse pmh1 mutant
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-191 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast mutants sep10 and sep15
The fission yeast Mcs6-Mcs2-Pmh1 complex (homologous to metazoan Cdk7-cyclin HMat1) performs dual functions: in cell cycle control, as a CDK-activating kinase; and in transcription by RNA polymerase (Pol) II, as part of TFIIH. It is unknown whether that linkage serves to coordinate gene expression w...
ORGANISM(S): Schizosaccharomyces pombe 
2004-11-01 | E-MEXP-193 | biostudies-arrayexpress
TranscriptomicsLong-Term Programming of Antigen-Specific Immunity from Gene Expression Signatures in the PBMC of Rhesus Macaques Immunized with an SIV DNA Vaccine
The primary objective of this study was to evaluate response to a SIV DNA-based vaccine that was adminstered via vivo electroporation (EP) in rhesus macaques to further understand the molecular correlates of protection against SIV. In this study, rhesus macaques were immunized with a DNA vaccine inc...
ORGANISM(S): Macaca mulatta 
2012-02-15 | E-GEOD-35816 | biostudies-arrayexpress
GenomicsPRMT5-mediated histone H4 arginine-3 symmetrical dimethylation marks chromatin at G+C-rich regions of the mouse genome.
Symmetrical dimethylation on arginine-3 of histone H4 (H4R3me2s) has been reported to occur at several repressed genes, but its specific regulation and genomic distribution remained unclear. Here, we show that the type-II protein arginine methyltransferase PRMT5 controls H4R3me2s in mouse embryonic ...
ORGANISM(S): Mus musculus domesticus x M. m. molossinus 
2013-10-04 | E-GEOD-37604 | biostudies-arrayexpress
Transcriptomics90 min Met4 hyperactivation ChIP-chip
Identification of in vivo binding targets of Met4 and Met32 by conducting chromatin immunoprecipitation studies using genomic tiling arrays (ChIP-on-chip 4X44K whole yeast genome arrays by Agilent) following 90 minutes Met4 hyperactivation.
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-21 | E-MEXP-3302 | biostudies-arrayexpress
GenomicsCell Type-Specific DNA Methylation at Intragenic CpG Islands in the Immune System (MAP-Seq and ChIP-Seq data)
Human and mouse genomes contain a similar number of CpG islands (CGIs), which are discrete CpG-rich DNA sequences associated with transcription start sites. In both species, about 50% of all CGIs are remote from annotated promoters, but nevertheless often have promoter-like features. To document the...
ORGANISM(S): Mus musculus 
2011-05-23 | E-GEOD-25688 | biostudies-arrayexpress
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