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TranscriptomicsArray CGH data of 64 prostate cancer specimens
The dataset comprises array CGH data of 64 prostate cancer specimens performed on Stanford cDNA microarrays, to accompany the study of J Lapointe et al (2007). For each array, Channel 2 represents Cy5-labeled prostate genomic DNA, and Channel 1 Cy3-labeled normal male genomic DNA. Set of arrays org...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-6469 | biostudies-arrayexpress
Transcriptomicswnt in human embryonic carcinoma cells
Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt pathway. Results We have identified target genes of Wnt signaling using microarray technology and human embryonal carcinom...
ORGANISM(S): Homo sapiens 
2005-09-08 | E-GEOD-3262 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wnt in human embryonic carcinoma cells
Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt pathway. Results We have identified target genes of Wnt signaling using microarray technology and human embryonal carcinom...
ORGANISM(S): Homo sapiens 
2005-09-02 | E-SMDB-1827 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of breast cancer cell lines defines relevant tumor models
This SuperSeries is composed of the following subset Series: GSE13914: Molecular profiling of breast cancer cell lines defines relevant tumor models (aCGH) GSE15361: Molecular profiling of breast cancer cell lines defines relevant tumor models (gene expression) Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-15376 | biostudies-arrayexpress
Transcriptomics5q21 tiling array on prostate tumors
CGH profiles of prostate tumors on custom designed high resolution arrays tiling chromosome 5q21 A custom high-density Agilent 15k CGH array tiling 5q21 was designed to narrow down the region of deletion at 5q21 to a few genes that could be followed up with functional studies. 8 critical prostate t...
ORGANISM(S): Homo sapiens 
2011-12-19 | E-GEOD-29228 | biostudies-arrayexpress
TranscriptomicsaCGH profiling of prostate tumors
This experiment was an aCGH study on 86 prostate tumors samples. The samples were profiled on Agilent Human Genome 44karrays to identify recurrent regions of deletion and amplification, thus revealing potential new tumor suppressor genes and/or oncogenes involved in prostate cancer. The CGH profile ...
ORGANISM(S): Homo sapiens 
2011-12-19 | E-GEOD-29227 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of prostate cells with CHD1 knockdown
Gene expression profiling of prostate tumor cells comparing cells that have CHD1 knockdown by shRNA (RWPE-1, OPCN2) or siRNA (LNCaP) with cells treated with non-targeted control. Prostate cell lines had CHD1 knockdown via shRNA or siRNA were hybridized against cells that were targeted with non-targe...
ORGANISM(S): Homo sapiens 
2011-12-19 | E-GEOD-33531 | biostudies-arrayexpress
TranscriptomicsCandidate prostate cancer genes through comparative expression-profiling of seminal vesicle
BACKGROUND: Prostate cancer is the most frequently diagnosed cancer among men in the United States. In contrast, cancer of the seminal vesicle is exceedingly rare, despite that the prostate and seminal vesicle share similar histology, secretory function, androgen dependency, blood supply, and (in p...
ORGANISM(S): Homo sapiens 
2008-05-08 | E-GEOD-11376 | biostudies-arrayexpress
TranscriptomicsProstate_5azadC
This microarray dataset accompanies the publication by Kim et al, "The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer". The dataset comprises four prostate cancer cell lines treated with the DNA methyltransferase inhibitor 5-aza-dC. For each cell line, gene...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-2932 | biostudies-arrayexpress
TranscriptomicsOvarian Cancer CGH
OBJECTIVES: Amplification of the 11q13 locus is commonly observed in a number of human cancers including both breast and ovarian cancer. Cyclin D1 and EMS1 have been implicated as candidate oncogenes involved in the emergence of amplification at this locus. Detailed analysis of the 11q13 amplicon in...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-16408 | biostudies-arrayexpress
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