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TranscriptomicsTranscription profiling of human cell lines under bioreductive prodrug PR-104A
A variety of human cell lines, were grown, RNA was extracted, and gene expression quantified using Affymetrix hgu133plus2 arrays. Expression of genes was compared to the rate of metabolism of the bioreductive prodrug PR-104A, and genes with expression shown to be statistically significantly correla...
ORGANISM(S): Homo sapiens 
2009-08-25 | E-TABM-767 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of desmoid tumor cells treated with gamma-secretase inhibitor
Desmoid tumors (DTs) are rare mesenchymal monoclonal lesions that have a high risk of local recurrence but lack metastatic potential. Since the Notch pathway appears to be important in the carcinogenesis of several tumor types, in the past few years γ-secretase inhibitors (GSIs) have emerged as a...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-61097 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lymph node sections from patients with Stage IIIB and IIIC melanoma and poor or good prognosis
Lymph node sections from 29 patients with StageIIIB and IIIC melanoma, with divergent clinical outcome including 16 poor and 13 good prognosis patients as defined by time to tumor progression (TTP), were profiled using MWG oligonucleotide arrays,.
ORGANISM(S): Homo sapiens 
2008-10-21 | E-TABM-403 | biostudies-arrayexpress
TranscriptomicsBudding yeast RNA polymerase II CTD phosphorylation and transcription termination factor localization
Whole genome analysis of total RNA pol II, Ser2-, Ser5- and Ser7-phosphorylated RNA pol II, in WT and mutants of the C-terminal domain (CTD) kinases Ctk1 and Kin28, and localization of the termination factors Pcf11, Nrd1 and Rat1. ChIP-chip using ligation-mediated PCR-amplified material hybridized t...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-15 | E-GEOD-23960 | biostudies-arrayexpress
TranscriptomicsTemporal Gene Expression Profiling during Rat Femoral Marrow Ablation-Induced Intramembranous Bone Regeneration
Enhanced understanding of differential gene expression and biological pathways associated with distinct phases of intramembranous bone regeneration following femoral marrow ablation surgery will improve future advancements regarding osseointegration of joint replacement implants, biomaterials design...
ORGANISM(S): Rattus norvegicus 
2010-10-12 | E-GEOD-22321 | biostudies-arrayexpress
TranscriptomicsMicroRNAs differentially expressed in liposarcoma
We performed expression profiling of microRNAs comparing liposarcomas (n=17) with normal fat pad (n=8). We found 35 miRNAs differentially expression (P<0.0001, fold>1.5), including mir-155. We performed expression profiling of microRNAs comparing liposarcomas with normal fat pad.
ORGANISM(S): Homo sapiens 
2012-03-22 | E-GEOD-31045 | biostudies-arrayexpress
UnknownTargeted copy number variant identification across the neurodegenerative disease spectrum.
Not available
S-EPMC9356547 | biostudies-literature
UnknownChanges in QTc interval in the citalopram for agitation in Alzheimer's disease (CitAD) randomized trial.
Not available
S-EPMC4051660 | biostudies-literature
UnknownEffect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial.
Not available
S-EPMC4086818 | biostudies-literature
UnknownNeuropsychiatric Symptom Burden across Neurodegenerative Disorders and its Association with Function.
Not available
S-EPMC10192827 | biostudies-literature
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