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The structure of the plk4 cryptic polo box reveals two tandem polo boxes required for centriole duplication.
Not available
S-EPMC3496063
|
biostudies-literature
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Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells.
Not available
S-EPMC10451095
|
biostudies-literature
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Targeting subcellular localization through the polo-box domain: non-ATP competitive inhibitors recapitulate a PLK1 phenotype.
Not available
S-EPMC3711794
|
biostudies-literature
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Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability.
Not available
S-EPMC4332252
|
biostudies-literature
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Polo-like kinase 1 (Plk1) inhibition synergizes with taxanes in triple negative breast cancer.
Not available
S-EPMC6872222
|
biostudies-literature
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Therapeutic targeting of Polo-like kinase-1 and Aurora kinases in T-cell acute lymphoblastic leukemia.
Not available
S-EPMC4111679
|
biostudies-literature
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New Insights Into the Role of Polo-Like Kinase 3 in Lung Tumorigenesis.
Not available
S-EPMC12904140
|
biostudies-literature
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Peptidomimetic Polo-Box-Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor.
Not available
S-EPMC7703809
|
biostudies-literature
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Asterless is a Polo-like kinase 4 substrate that both activates and inhibits kinase activity depending on its phosphorylation state.
Not available
S-EPMC6249866
|
biostudies-literature
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Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni.
Not available
S-EPMC4709140
|
biostudies-literature
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