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Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the environment as components of fossil fuels and by-products of combustion. These multi-ring chemicals differentially activate the Aryl Hydrocarbon Receptor (AHR) in a structurally-dependent manner, and induce toxicity via both AHR-dependent...
ORGANISM(S): Danio rerio 
Anaerobic degradation of polyaromatic hydrocarbons coupled to Fe(III) oxide reduction: community dynamics and isolated strains
Petroleum substances are complex mixtures of hydrocarbons with vast structural diversity, posing significant challenges for toxicity assessment. To evaluate their safety under the REACH legislation, in vivo toxicological tests, particularly prenatal developmental toxicity assessments, are mandated. ...
ORGANISM(S): Rattus norvegicus 
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