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ProteomicsMitochondrial leakage and mtDNA damage triggering early immune response in Inclusion Body Myositis.
Polymyositis with mitochondrial pathology (PM-Mito) was first identified in 1997 as a subtype of idiopathic inflammatory myopathy (IIM). Significant molecular similarities have been recently detected between PM-Mito and Inclusion Body Myositis (IBM), suggesting a trajectory from early to full-blown ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD053742 | Pride
Polymyositis with mitochondrial pathology  pm-mito  ibm-sd  mitochondria 
ProteomicsProteomic Profiles in Inclusion Body Myositis and Polymyositis with Mitochondrial Pathology: A Comparative Study Across Idiopathic Inflammatory Myopathies
Idiopathic inflammatory myopathies (IIMs) encompass a diverse group of autoimmune disorders affecting skeletal muscle, including dermatomyositis (DM), anti-synthetase syndrome (ASyS), immune-mediated necrotizing myopathy (IMNM), and inclusion body myositis (IBM). Polymyositis with mitochondrial path...
ORGANISM(S): Homo Sapiens (human) 
2026-05-12 | PXD063841 | JPOST Repository
UnknownA Mutation in the Mitochondrial Aspartate/Glutamate Carrier Leads to a More Oxidizing Intramitochondrial Environment and an Inflammatory Myopathy in Dutch Shepherd Dogs.
Not available
S-EPMC6918910 | biostudies-literature
UnknownClinicopathological and circulating cell-free DNA profile in myositis associated with anti-mitochondrial antibody.
Not available
S-EPMC10647000 | biostudies-literature
UnknownMitochondrial dysfunction and role of harakiri in the pathogenesis of myositis.
Not available
S-EPMC7219509 | biostudies-literature
UnknownRole of mitochondria in the myopathy of juvenile dermatomyositis and implications for skeletal muscle calcinosis.
Not available
S-EPMC10330803 | biostudies-literature
UnknownRyanodine receptor type 1 content decrease-induced endoplasmic reticulum stress is a hallmark of myopathies.
Not available
S-EPMC10751419 | biostudies-literature
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