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Transcriptomicsc-Myc supports polyploidy and prevents senescence in the murine placenta [scRNA-Seq]
Placenta is essential for reproductive success and placental abnormalities are the leading cause of low birth weight and preterm birth. The placenta includes polyploid cells that are crucial for its function. Polyploidy occurs broadly in nature but the regulators that enable polyploidy to arise in a...
ORGANISM(S): Mus musculus 
2023-05-12 | GSE215381 | GEO
UnknownSpatial ploidy inference using quantitative imaging.
Not available
S-EPMC12859483 | biostudies-literature
GenomicsSomatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output [RNA-seq]
Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output [RNA-seq]
PRJNA1181026 | ENA
UnknownDoes polyploidy facilitate long-distance dispersal?
Not available
S-EPMC4030813 | biostudies-literature
UnknownPolyploidy can drive rapid adaptation in yeast.
Not available
S-EPMC4497379 | biostudies-literature
GenomicsSomatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output [ChIP-seq]
Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output [ChIP-seq]
PRJNA1181025 | ENA
UnknownConserved chamber-specific polyploidy maintains heart function in Drosophila.
Not available
S-EPMC10482010 | biostudies-literature
UnknownPolyploidy in the adult Drosophila brain.
Not available
S-EPMC7447450 | biostudies-literature
UnknownRevisiting ancient polyploidy in leptosporangiate ferns.
Not available
S-EPMC7614084 | biostudies-literature
GenomicsSomatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output [ChIP-seq]
Cell size and biosynthetic capacity generally increase with increased DNA content. Somatic polyploidy has therefore been proposed to be an adaptive strategy to increase cell size in specialized tissues with high biosynthetic demands. However, if and how DNA concentration limits cellular biosynthesis...
ORGANISM(S): Caenorhabditis elegans 
2024-11-03 | GSE280912 | GEO
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