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MetabolomicsFunctional specialization of bacterial cellular and extracellular fractions contributes to polysaccharide degradation

Bacteroides thetaiotaomicron (Bt), a key commensal of the human gut microbiota, exhibits robust capacity to degrade dietary polysaccharides via carbohydrate-active enzymes (CAZymes). However, the exact spatial distribution and the functional coordination of these enzymes remain poor...

2026-03-27 | MTBLS14156 | MetaboLights
TranscriptomicsCoordinate regulation of glycan degradation and polysaccharide capsule biosynthesis by a prominent human gut symbiont
Analysis of B. thetaiotaomicron trans-envelope signaling mutants in ECF-sigma factors, anti-sigma factors and SusC-like transporters. B. thetaiotaomicron mutants were transcriptionally profiled after growth in vitro in either minimal medium plus glucose or minimal medium plus neutral O-glycans
ORGANISM(S): Bacteroides thetaiotaomicron VPI-5482 
2010-05-18 | E-GEOD-14592 | biostudies-arrayexpress
TranscriptomicsA comparative systems analysis of polysaccharide-elicited responses in Neurospora crassa reveals carbon source-specific cellular adaptations
Filamentous fungi are powerful producers of hydrolytic enzymes for the deconstruction of plant cell wall polysaccharides. However, the central question of how these sugars are perceived in the context of the complex cell wall matrix remains largely elusive. To address this question in a systematic f...
ORGANISM(S): Neurospora crassa OR74A 
2013-11-27 | E-GEOD-42692 | biostudies-arrayexpress
TranscriptomicsCis-encoded sRNAs repress expression of polysaccharide utilization loci in Bacteroides fragilis 638R
The phylum Bacteroidetes is a major component of the human gut microbiota which has a broad impact on the development and physiology of its host, and a potential role in a wide range of disease syndromes1-3. The predominance of Bacteroidetes and the genus Bacteroides in the distal gut is due in larg...
ORGANISM(S): Bacteroides fragilis 638R 
2016-07-22 | E-GEOD-73107 | biostudies-arrayexpress
TranscriptomicsIntestine-adapted bacterial symbiont response to polysaccharide rich and polysaccharide deficient diets in mice lacking fucosyltransferase-2
Analysis of Bacteroides thetaiotaomicron (BT) from the ceca of ex-germ free Fut2+ or Fut2- mice on polysaccharide rich or glucose rich polysaccharide deficient diet. BT is involved in the breakdown of plant polysaccharides and is also efficiently utilizes host glycans. BT-colonized mice represent a ...
ORGANISM(S): Bacteroides thetaiotaomicron 
2014-04-21 | E-GEOD-45641 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of Bacteroides xylanisolvens XB1AT grown on pectin or xylan
Dietary fiber degradation is a key function of the human gut microbiota. The aim of this study was to increase our knowledge on the degradation of plant cell wall polysaccharide degradation by a prominent human gut bacterial species, Bacteroides xylanisolvens. The transcriptome analysis of B. xylan...
ORGANISM(S): Bacteroides xylanisolvens 
2015-10-28 | E-GEOD-74379 | biostudies-arrayexpress
UnknownMapping the polysaccharide degradation potential of Aspergillus niger.
Not available
S-EPMC3542576 | biostudies-literature
TranscriptomicsBiphasic polysaccharide metabolism of Alteromonas macleodii 83-1 analyzed by RNA-Seq
Polysaccharides from macroalgae are important bacterial nutrient source and central biogeochemical component in the oceans. To illuminate the cellular mechanisms of polysaccharide degradation by marine bacteria, growth of Alteromonas macleodii 83-1 on a mix of laminarin, alginate and pectin was char...
ORGANISM(S): Alteromonas macleodii 
2018-08-01 | GSE107306 | GEO
UnknownPhosphate deprivation restricts bacterial degradation of the marine polysaccharide fucoidan.
Not available
S-EPMC12872454 | biostudies-literature
UnknownDistribution and diversity of enzymes for polysaccharide degradation in fungi.
Not available
S-EPMC5428031 | biostudies-literature
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