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TranscriptomicsComparing isogenic pairs of hESC and hiPSC lines reveals genetic background and reprogramming method as primary sources of transcriptional variation
The equivalency of human induced pluripotent stem cells (hiPSCs) with human embryonic stem cells (hESCs) remains controversial. Here, we devised a strategy to assess the contribution of clonal growth, reprogramming method and genetic background to transcriptional patterns in hESCs and hiPSCs. Surpri...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-73211 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse colon to investigate how suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity
Mice with colonic tumors (chemically induced by AOM/DSS) were treated with Nutlin or control vehicle solution to analyze p53 target gene expression in vivo.
ORGANISM(S): Mus musculus 
2021-04-20 | E-MTAB-10041 | biostudies-arrayexpress
TranscriptomicsSuppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity
p53LOH in murine CRC organoids de-represses HSF1 activity and triggers mutp53-driven invasion.
ORGANISM(S): Mus musculus 
2021-05-17 | E-MTAB-10416 | biostudies-arrayexpress
UnknownImpact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry.
Not available
S-EPMC8527730 | biostudies-literature
UnknownClinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry.
Not available
S-EPMC9440492 | biostudies-literature
UnknownImpact of renal impairment on atrial fibrillation: ESC-EHRA EORP-AF Long-Term General Registry.
Not available
S-EPMC9287022 | biostudies-literature
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