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MetabolomicsA non-dividing population with high pyruvate dehydrogenase kinase activity drives metabolic heterogeneity and tumorigenesis in the intestine
Not available
ORGANISM(S): Mus musculus 
ST002072 | MetabolomicsWorkbench
MetabolomicsMetabolic heterogeneity in Glioblastoma
Not available
ORGANISM(S): Homo sapiens 
ST000248 | MetabolomicsWorkbench
MetabolomicsCell-to-cell heterogeneity drives host-virus coexistence in a bloom-forming alga

Algal blooms drive global biogeochemical cycles of key nutrients in the oceans and serve as hotspots for biological interactions. The massive spring blooms of the cosmopolitan coccolithophore Emiliania huxleyi (E. huxleyi) are often infected by the lytic Emiliania huxleyi

2024-01-04 | MTBLS1956 | MetaboLights
MetabolomicsSingle-cell time-resolved multi-omics reveal apoptotic and ferroptotic heterogeneity during foam cell formation

Macrophage-derived foam cell plays a pivotal role in the plaque formation and rupture during the progression of atherosclerosis. Foam cells are destined to divergent cell fate and functions in response to external stimuli based on their internal states, which however is hidden in the traditional ...

2023-09-08 | MTBLS6366 | MetaboLights
MetabolomicsSingle-cell thiol profiling enabled by live-cell labeling reveals metabolic heterogeneity in ferroptosis

Raw data of both bulk and single-cell metabolomics. It includes all MS, LC-MS and LC-MS/MS raw data associated with the article 'Single-cell thiol profiling enabled by live-cell labeling reveals metabolic heterogeneity in ferroptosis'.

2026-02-14 | MTBLS13900 | MetaboLights
MetabolomicsRhizosphere microorganism and leaf metabolomics explain the adaption and habitat heterogeneity of two Zoysia species from the Yellow River Delta
This study investigates the metabolic responses of two Zoysia species (Z. macrostachya and Z. sinica) adapted to distinct microhabitats in the Yellow River Delta. Leaf samples were collected from natural populations growing under different saline-alkaline conditions. Untargeted metabolomics was perf...
2026-07-13 | MTBLS15027 | MetaboLights
TranscriptomicsGenetic Heterogeneity in Mouse Mammary Tumors
Human cancers result from a complex series of genetic alterations resulting in heterogeneous disease states. Dissecting this heterogeneity is critical for understanding underlying mechanisms and providing opportunities for therapeutics matching the complexity. Mouse models of cancer have generally b...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-15904 | biostudies-arrayexpress
ProteomicsNannochloropsis oceanica cultivations display phenotypic heterogeneity in lipid metabolism
By combination of FACS sorting based on lipid sensitive Nile Red staining and small cell number proteomics the occurrence of population heterogeneity was analyzed. First population heterogeneity was identified by Nile Red staining and FACS in N. oceanica cells grown in nitrogen replete and nitrogen ...
ORGANISM(S): Nannochloropsis oceanica strain IMET1 
2019-02-15 | PXD008721 | Pride
Population heterogeneity  nannochloropsis oceanica  lipid metabolism  small cell number proteomics 
TranscriptomicsCell cycle positioning drives heterogeneity within the pluripotent stem cell compartment
Heterogeneity in pluripotent cells marks a metastable state where cells may drift between native and lineage-primed populations. While the role for these heterogeneities are unclear, they may reflect the dynamic equilibriums of signaling networks and have a direct effect on differentiation potentia...
ORGANISM(S): Homo sapiens 
2013-12-19 | E-GEOD-53481 | biostudies-arrayexpress
TranscriptomicsReactivation of multipotency by oncogenic PIK3CA induces breast tumor heterogeneity
Breast cancer is the most frequent cancer in women and consists of heterogeneous types of tumours that are classified into different histological and molecular subtypes1-3. Pik3ca and p53 are the two most frequently mutated genes and are associated with different types of human breast cancers4. The ...
ORGANISM(S): Mus musculus 
2015-08-13 | E-GEOD-69290 | biostudies-arrayexpress
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