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TranscriptomicsStrand-specific transcriptome profiles of the oral pathogen Porphyromonas gingivalis using genomic tiling microarray and RNA sequencing
High-density tiling microarray and RNA sequencing technologies were used to analyze the transcriptome of Porphyromonas gingivalis. The compiled P. gingivalis transcriptome were based on total RNA samples isolated from three different laboratory culturing conditions and the strand-specific transcript...
ORGANISM(S): Porphyromonas gingivalis W83 
2011-10-01 | E-GEOD-30452 | biostudies-arrayexpress
TranscriptomicsPorphyromonas gingivalis gene expression during co-culture with Treponema denticola
Porphyromonas gingivalis and Treponema denticola are periodontalpathogens that are associated with the severity and progression of periodontal diseases. This study investigates the gene expression of Porphyromonas gingivalis during co-culture with Treponema denticola
ORGANISM(S): Porphyromonas gingivalis 
2014-03-31 | E-MTAB-2214 | biostudies-arrayexpress
TranscriptomicsHuman Trophoblast Responses to P. gingivalis Infection
Porphyromonas gingivalis is a periodontal pathogen that is also associated with preterm low birth weight delivery. We investigated the transcriptional responses of human extravillous trophoblasts (HTR-8) to infection with P. gingivalis. Over 2000 genes were differentially regulated in HTR-8 cells ...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-19810 | biostudies-arrayexpress
TranscriptomicsTreponema denticola gene expression during co-culture with Porphyromonas gingivalis
Porphyromonas gingivalis and Treponema denticola are periodontalpathogens that are associated with the severity and progression of periodontal diseases. this study investigates the gene expression of Treponema denticola during co-culture with Porphyromonas gingivalis.
ORGANISM(S): Treponema denticola 
2014-03-31 | E-MTAB-2257 | biostudies-arrayexpress
TranscriptomicsHigh-throughput sequencing reveals key genes and immune homeostatic pathways activated in myeloid dendritic cells by Porphyromonas gingivalis 381 and its fimbrial mutants
Periodontitis affects 47.1% of adult population in the U.S. Porphyromonas gingivalis is an opportunistic oral pathogen that colonizes the oral mucosa, invades myeloid dendritic cells and accesses the bloodstream, brain, placenta and other organs in human with periodontitis. Periodontitis also sustai...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-67141 | biostudies-arrayexpress
TranscriptomicsPorphyromonas gingivalis comparative genomic hybridization
Genotyping studies suggest that there is genetic variability among P. gingivalis strains, however the extent of variability remains unclear, and the regions of variability have only partially been identified. We previously used heteroduplex analysis of the ribosomal operon intergenic spacer region (...
ORGANISM(S): Porphyromonas gingivalis 
2010-05-18 | E-GEOD-13128 | biostudies-arrayexpress
TranscriptomicsGene expression data from P. gingivalis infected Mouse
The objectives of this investigation were to examine changes in the host transcriptional profiles during a Porphyromonas gingivalis infection using a murine calvarial model of inflammation and bone resorption. P. gingivalis strain 381 was injected into the subcutaneous soft tissue over the calvaria...
ORGANISM(S): Mus musculus 
2010-07-15 | E-GEOD-17110 | biostudies-arrayexpress
TranscriptomicsResponse of Porphyromonas gingivalis to nitrosative stress
Transcriptional profiling of P. gingivalis cells comparing cells grown in anaerobic conditions to cells grown in anaerobic conditions and exposed to nitrite and to GSNO. Two-condition experiment, anaerobically vs. anaerobically exposed to nitrosative stress cells. Biological replicates: 1 independen...
ORGANISM(S): Porphyromonas gingivalis 
2012-10-05 | E-GEOD-38220 | biostudies-arrayexpress
TranscriptomicsAnalysis of gene expression in Porphyromonas gingivalis hmuS deletion mutant strain (RNA-seq analysis)
Porphyromonas gingivalis is considered a keystone pathogen responsible for dysbiosis in the oral microbiome, leading to the development of periodontal disease and contributing to various systemic comorbidities. Although P. gingivalis requires heme for growth and virulence, it is unable to synthesize...
ORGANISM(S): Porphyromonas gingivalis 
2026-04-24 | E-MTAB-16197 | biostudies-arrayexpress
TranscriptomicsPorphyromonas gingivalis: Control (Wild-type W83) vs. its htrA mutant
Transcriptional profiling of the wild-type and its htrA mutant. Identification of genes that are affected by the htrA mutation in P. gingivalis Keywords: Genetic modification Two-condition experiment, W83 vs. htrA mutant late-log growth phase. Biological replicates: 4 control, 4 mutant, independentl...
ORGANISM(S): Porphyromonas gingivalis 
2010-05-26 | E-GEOD-10027 | biostudies-arrayexpress
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