Sort   by:  
 Page size 
ProteomicsQuantitative Single-Cell Proteomics as a Tool to Characterize Cellular Hierarchies
Large-scale single-cell analyses are of fundamental importance in order to capture biological heterogeneity within complex cell systems, but have largely been limited to RNA-based technologies. Here we present a comprehensive benchmarked experimental and computational workflow, which establishes glo...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-10-21 | MSV000090570 | MassIVE
ProteomicsThe p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promoting factor CD73 in CEBPA mutant AML
The key myeloid transcription factor (TF) CEBPA is frequently mutated in acute myeloid leukemia (AML), but the molecular ramifications of this leukemic driver mutation remain elusive. To investigate CEBPA mutant AML, we compared gene expression changes in human CEBPA mutant AML and in the correspond...
ORGANISM(S): Mus musculus (Mouse) 
2019-08-08 | PXD011359 | Pride
Cebpa Global proteomics Acute myeloid leukemia 
GenomicsAmplification of pico-scale DNA mediated by bacterial carrier DNA for small-cell-number transcription factor ChIP-seq
ChIP-seq is used to map transcription factor occupancy and generate epigenetic profiles genome-wide. The requirement of nano-scale ChIP DNA for generation of sequencing libraries has impeded ChIP-seq on in vivo tissues of low cell numbers. We describe a robust, simple and scalable methodology for Ch...
ORGANISM(S): Mus musculus 
2015-02-01 | E-GEOD-55850 | biostudies-arrayexpress
GenomicsTemporal mapping of C/EBPα and –β binding during liver regeneration
Temporal mapping of C/EBPα and –β binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries. Timeseries ChIP-seq of transcription factors C/EBPα and –β, and Pol II in time points 0, 3, 8, 16, 24, 36, 48, 168 hours after pa...
ORGANISM(S): Mus musculus 
2013-01-24 | E-GEOD-42321 | biostudies-arrayexpress
Sort   by:  
 Page size