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UnknownPortacaval anastomosis promotes fragmentation of mitochondrial network in the cerebellum of male rats.
Not available
S-EPMC12460505 | biostudies-literature
TranscriptomicsGene Expression of brain cortex microvessels in two rat models of acute liver failure (ALF)
Evaluation of early transcriptional changes in blood brain barrier genes involved in the patogenesis of brain edema associated with ALF. Two different well stablished rat models were analyzed: Portacaval anastomosis plus hepatic artery ligation and portacaval anastomosis plus total hepatectomy.
ORGANISM(S): Rattus norvegicus 
2016-04-05 | GSE79906 | GEO
UnknownRecovery from Liver Failure and Fibrosis in a Rat Portacaval Anastomosis Model after Neurointermediate Pituitary Lobectomy.
Not available
S-EPMC8677405 | biostudies-literature
TranscriptomicsGene Expression of brain cortex microvessels in two rat models of acute liver failure (ALF)
Evaluation of early transcriptional changes in blood brain barrier genes involved in the patogenesis of brain edema associated with ALF. Two different well stablished rat models were analyzed: Portacaval anastomosis plus hepatic artery ligation and portacaval anastomosis plus total hepatectomy. ALF ...
ORGANISM(S): Rattus norvegicus 
2016-04-05 | E-GEOD-79906 | biostudies-arrayexpress
ProteomicsMitochondrial responses during hyperammonemia
Ammonia is a cytotoxic metabolite with pleotropic molecular and metabolic effects in non-hepatic tissue/cells targeting mitochondrial oxidative function that may contribute to post-mitotic senescence. Global molecular responses were determined by analysis of unbiased data followed by experimental va...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2022-02-17 | PXD026955 | Pride
Cytotoxic Ammonia Pca Hyperammonemia Portacaval anastomosis 
ProteomicsMetabolic reprogramming during hyperammonemia targets mitochondrial function and post-mitotic senescence
Ammonia is a cytotoxic metabolite with pleotropic molecular and metabolic effects in non-hepatic tissue/cells targeting mitochondrial oxidative function that may contribute to post-mitotic senescence. Global molecular responses were determined by analysis of unbiased data followed by experimental va...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2021-11-22 | PXD027754 | Pride
Cytotoxic Ammonia Pca Hyperammonemia Portacaval anastomosis 
UnknownCerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy.
Not available
S-EPMC5363476 | biostudies-literature
GenomicsRattus norvegicus
Gene Expression of brain cortex microvessels in two rat models of acute liver failure (ALF)
PRJNA317351 | ENA
UnknownAmmonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis.
Not available
S-EPMC5444955 | biostudies-literature
UnknownMetabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence.
Not available
S-EPMC8783680 | biostudies-literature
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