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ProteomicsMitochondrial alternative NADH dehydrogenases limit ROS, protect chloroplasts and promote survival of reoxygenation in Arabidopsis
Weather extremes are increasing worldwide frequently exposing plants to transient flooding. When floodwaters recede, plants have to cope with increased light intensity and elevated oxygen that favor excessive formation of reactive oxygen species (ROS). We report a novel molecular mechanism that help...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2022-12-02 | PXD032119 | JPOST Repository
ProteomicsThe Nα-acetyltransferase NAA50 mediates plant immunity independent of the NatA complex
Nα-terminal acetylation (NTA) ranges among the most abundant protein modifications in higher eukaryotes. Over 40 % of the human and plant proteome are co-translationally acetylated by a single Nα-acetyltransferase (Nat) termed NatA. The core NatA complex consists of the catalytic subunit NAA10 and t...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2024-03-01 | PXD040755 | JPOST Repository
TranscriptomicsSuppression of antitumor immunity by the oncometabolite 2-hydroxyglutarate
Isocitrate dehydrogenase (IDH) mutations, a hallmark of gliomagenesis, result in the production of the oncometabolite R-2-hydroxyglutarate (R-2-HG) which is thought to promote tumorigenesis via DNA methylation. Here we identify an additional immunosuppressive activity of R-2-HG: Tumor cell-derived R...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-84849 | biostudies-arrayexpress
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