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TranscriptomicsGene expression in IGROV1 SP and non-SP cells
Side populations have recently been identified in ovarian cancers and may play an important role in post treatment relapse and resistance to chemotherapeutic drugs. In this study, we aimed to identify the differential expression between IGROV1 SP and NSP on Affymetrix HG-U133plus2 microarrays. We fo...
ORGANISM(S): Homo sapiens 
2011-02-09 | E-GEOD-25191 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human conjunctival epithelial side population cells
Side population (SP) cells isolated from limbal and conjunctival epithelia derive from cells that are slow cycling in vivo, a known feature of tissue stem cells. The purpose of this study was to define the molecular signature of the conjunctival side population cells by global differential gene expr...
ORGANISM(S): Homo sapiens 
2009-11-11 | E-GEOD-12631 | biostudies-arrayexpress
TranscriptomicsExpression data from HTR-8/Svneo side population (SP) and non-side population (NSP) cells
Immature cell populations, including stem cells and progenitor cells, can be found in M-bM-^@M-^\side-population (SP)M-bM-^@M-^] cells. Although SP cells isolated from some adult tissues have been reported elsewhere, isolation and characterization of human trophoblast SP cells remained to be reporte...
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-61547 | biostudies-arrayexpress
ProteomicsHDL proteome remodeling post-stroke
Prospective cohort studies and meta-analyses examining the relationship between HDL-cholesterol (C) and stroke risk are discordant and question the value of HDL-C as a marker for stroke risk prediction. However, the relationship between other metrics of HDL, function and proteome, and stroke remain ...
ORGANISM(S): Homo Sapiens 
2021-01-24 | PXD015001 | panorama
TranscriptomicsHUMAN ENDOMETRIAL SIDE POPULATION CELLS EXHIBIT GENOTYPIC, PHENOTYPIC AND FUNCTIONAL FEATURES OF SOMATIC STEM CELLS
During reproductive life, the human endometrium undergoes around 480 cycles of growth, breakdown and regeneration should pregnancy not be achieved. This outstanding regenerative capacity is the basis for women’s cycling and its dysfunction may be involved in the etiology of pathological disorders. T...
ORGANISM(S): Homo sapiens 
2010-08-15 | E-GEOD-21633 | biostudies-arrayexpress
TranscriptomicsSperm mRNA transcripts are indicators of sub-chronic low dose testicular injury in the Fischer 344 rat
Current human reproductive risk assessment methods rely on semen and serum hormone analyses, which are not easily comparable to the histopathological endpoints and mating studies used in animal testing. Because of these limitations, there is a need to develop universal evaluations that reliably refl...
ORGANISM(S): Rattus norvegicus 
2012-09-01 | E-GEOD-34641 | biostudies-arrayexpress
TranscriptomicsPost-replicative formation of cohesion is required for repair and induced by a single DNA break
Sister chromatid cohesion, established during replication by the protein complex Cohesin, is essential for both chromosome segregation and double-strand break (DSB) repair. Normally cohesion formation is strictly limited to the S-phase of the cell cycle, but DSBs can trigger cohesion also after DNA ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-8270 | biostudies-arrayexpress
TranscriptomicsSequencing of the transcriptome from embryonic and larval hemocytes in gcm knock down background
Hemocytes were sorted from stage 16 embryos and wandering 3rd instar larvae in which gcm was knocked down using gcmRNAi and the driver srp(hemo)Gal4. The experiments were done in triplicate. The wild type controls at stage 16 embryo and wandering larvae are available under this assession number: E-M...
ORGANISM(S): Drosophila melanogaster 
2022-10-18 | E-MTAB-11966 | biostudies-arrayexpress
TranscriptomicsOmeprazole stimulated gene expression in rats
Omeprazole stimulated gene expression in rats Samples and RNA preparation: The series is composed of 9 hybridizations for analysis of differentially expressed genes in the gastric mucosa of omeprazole dosed vs. control rats. Nine rats (200-250 g) were given (by gavage) 400 micromol/kg of the proton ...
ORGANISM(S): Rattus norvegicus 
2010-06-05 | E-GEOD-1808 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of BrO, DMGO and GD2 CAR T cells
Diffuse midline glioma (DMG) is a lethal pediatric brain cancer with limited treatment options. We developed a human brainstem organoid model to study H3.3K27M-driven DMG, enabling formation of patient-like tumors with molecular heterogeneity. To characterize this model, we performed a time-course t...
ORGANISM(S): Homo sapiens 
2025-08-28 | E-MTAB-15147 | biostudies-arrayexpress
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